ArticleThe journal of physiological sciences : JPS2016
Partial cavopulmonary assist from the inferior vena cava to the pulmonary artery improves hemodynamics in failing Fontan circulation: a theoretical analysis.
Article in The journal of physiological sciences : JPS, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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6 citing papers in PubMed.
- Effects of systemic ventricular assist combined with fenestration in failing Fontan: A theoretical analysis.The journal of physiological sciences : JPS · 2026Article
- Evaluation of the effects of fenestration in Fontan circulation using a lumped parameter model.The journal of physiological sciences : JPS · 2024Article
- Dielectric elastomer actuator-based valveless pump as Fontan failure assist device: introduction and preliminary study.Interdisciplinary cardiovascular and thoracic surgery · 2024Article
- Lumped parameter model for hemodynamic simulation of congenital heart diseases.The journal of physiological sciences : JPS · 2018Review
- Heart transplantation for adults with congenital heart disease: current status and future prospects.General thoracic and cardiovascular surgery · 2017Review
- Review of cardiac-coronary interaction and insights from mathematical modeling.WIREs mechanisms of diseaseReview
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8 authors.
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Abstract
Cavopulmonary assist (CPA) for failing Fontan patients remains a challenging issue in the clinical setting. To evaluate the effectiveness of a partial CPA from the inferior vena cava (IVC) to the pulmonary artery (PA), we performed a theoretical analysis using a computational model of the Fontan circulation. Cardiac chambers and vascular systems were described as the time-varying elastance model and the modified three-element Windkessel model, respectively. A rotational pump described as a non-linear function was inserted between the IVC and the PA. When pulmonary vascular resistance index varied from 2.1 to 5.9 Wood units m(2), the partial CPA maintained cardiac index as efficiently as total CPA and markedly reduced the IVC pressure compared with total CPA. However, the partial CPA increased the superior vena cava pressure substantially. The modification from total to partial CPA is potentially an effective alternative in failing Fontan patients suffering from high IVC pressure.
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