ArticleBMC neurology2015
Surgical resection of unilateral thalamic tumors in adults: approaches and outcomes.
Article in BMC neurology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 2 syntheses or guidelines pooled it, 46 citations in OpenAlex.
- Pineal Region Gliomas: A Systematic Review of Clinical Features and Treatment Outcomes.Anticancer research · 2022Pooled it
- Thalamic gliomas in adults: a systematic review of clinical characteristics, treatment strategies, and survival outcomes.Journal of neuro-oncology · 2021Pooled it
- Stereotactic Radiosurgery for Thalamic Brain Metastases: A Retrospective Analysis and Literature Review.Neurosurgery practice · 2026Article
- The clinical and molecular landscape of thalamic glioma.Neuro-oncology · 2026Article
- Modified tubular retractor for deep brain tumour resection: enhanced surgical outcomes in resource-constrained settings.Neurosurgical review · 2026Article
- Survival analysis of adult midline-located gliomas and diffuse midline gliomas: beyond the H3K27 mutation paradigm.Journal of neuro-oncology · 2026Article
- Anatomical and surgical technical aspects of intraparietal sulcus approach for posterolateral thalamic glioma: illustrative case.Journal of neurosurgery. Case lessons · 2025Article
- Clinical and survival differences between thalamic glioblastoma and thalamic diffuse midline glioma, H3 K27-altered.Journal of neuro-oncology · 2025Article
- The impact of maximized resection and standardized systemic therapy on overall survival in adult patients with thalamic gliomas.Frontiers in oncology · 2025Article
- High-Grade Thalamic Glioma: Case Report with Literature Review.Medicina (Kaunas, Lithuania) · 2024Review
- The 2021 World Health Organization Central Nervous System Tumor Classification: The Spectrum of Diffuse Gliomas.Biomedicines · 2024Review
- Long-Term Outcomes and Survival Rates of Patients Undergoing Biopsy Vs. Maximum Safe Resection for Thalamic Lesions: A Short Review on Current Evidence.Galen medical journal · 2024Review
- Article
- LITTing up Gliomas-Is the Future Bright?World neurosurgery: X · 2023Article
- Clinical Characteristics and Prognostic Risk Factors of Parasellar Chondrosarcoma.Brain sciences · 2022Article
- Risk Factors for Early Hydrocephalus on Post Unilateral Thalamic Tumor Resection.Frontiers in surgery · 2022Article
- Evolution of surgical attitudes to paediatric thalamic tumours: the alder hey experience.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2021Review
- Parietal interhemispheric transfalcine transtentorial approach for posterior incisural space lesions: from the lab to the operative room.Neurosurgical review · 2021Article
- Maximal surgical resection and adjuvant surgical technique to prolong the survival of adult patients with thalamic glioblastoma.PloS one · 2021Article
- In Reply: Thalamic Glioblastoma: Clinical Presentation, Management Strategies, and Outcomes.Neurosurgery · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundThe thalamic tumors were less common in adults and this study aimed to determine the clinical features, surgical approaches, and outcomes of adult thalamic tumors, which have not been well-described in the literature.
methodsWe reviewed the clinical presentation, surgical approach, perioperative mortality and morbidity, and outcomes of 111 operated patients (71 males, 40 females; mean age at presentation, 33.4 ± 13.2 years) with unilateral thalamic tumor.
resultsThe most common clinical presentations were increased intracranial pressure (65%) and motor deficits (40%). Five surgical approaches were used depending on tumor location; the most common was the transparieto-occipital approach (47.7%). According to peri- and post-operative magnetic resonance imaging findings, the tumors were totally resected in 29 cases (26.1%), subtotally resected in 54 cases (48.6%), and partially resected in 21 cases (18.9%). Five patients died during the perioperative period (4.5%, 5/111). The most common morbidity was motor deficits (21.7%, 23/106). According to histological findings, there were 50 high-grade and 61 low-grade tumors. Median survival of patients with low- and high-grade tumors were 40 and 12 months, respectively (mean follow-up, 37.3 months). Survival was significantly longer in cases of total or subtotal resection (median, 28 months) compared to partial resection or biopsy (median, 12 months). Survival was poorer in adults than in previous reported pediatrics.
conclusionsSurgical treatment of adult thalamic tumors must be individualized according to tumor location. Low-grade tumors and total/subtotal resection seem to be predictors of better surgical outcomes. Nevertheless, the outcome of adult patients were still worse than pediatric patients.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.