ArticlePloS one2015
Optic Disc - Fovea Angle: The Beijing Eye Study 2011.
Article in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
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Who cites it
32 citing papers in PubMed, 71 citations in OpenAlex.
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- Cyclotorsion as a structural and functional biomarker of ocular and neuroophthalmic diseases.Acta biochimica Polonica · 2026Review
- Short-Term Changes in Peripapillary RNFL and Disc-Fovea Angle After Horizontal Rectus Muscle Surgery in Comitant Strabismus.Clinical ophthalmology (Auckland, N.Z.) · 2026Article
- Article
- Assessment of Objective Cyclotorsion Changes Following Symmetric and Asymmetric Graded Recession of Inferior Oblique Muscle for V-Pattern Strabismus.Clinical ophthalmology (Auckland, N.Z.) · 2025Article
- Retinal Changes From Hyperopia to Myopia: Not All Diopters Are Created Equal.Investigative ophthalmology & visual science · 2024Article
- Controlling the input: How one-year-old infants sustain visual attention.Developmental science · 2024Article
- Evaluation of the Diagnostic Capability of Spectralis SD-OCT 8 × 8 Posterior Pole Software with the Grid Tilted at 7 Degrees and Horizontalized in Glaucoma.Journal of clinical medicine · 2024Article
- IMI-Nonpathological Human Ocular Tissue Changes With Axial Myopia.Investigative ophthalmology & visual science · 2023Article
- Asymmetry of Peripapillary Retinal Blood Vessel and Retinal Nerve Fiber Layer Thickness Between Healthy Right and Left Eyes.Investigative ophthalmology & visual science · 2023Article
- Assessing the external validity of machine learning-based detection of glaucoma.Scientific reports · 2023Article
- Deep Learning Model for Static Ocular Torsion Detection Using Synthetically Generated Fundus Images.Translational vision science & technology · 2023Article
- Effectiveness of modified inferior oblique muscle belly transposition for V-pattern exotropia combined with mild to moderate inferior oblique muscle overaction.International journal of ophthalmology · 2023Article
- Comparison of subjective cyclofusion ranges and objective ocular torsion in normal participants according to age.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2022Article
- A multi-regression approach to improve optical coherence tomography diagnostic accuracy in multiple sclerosis patients without previous optic neuritis.NeuroImage. Clinical · 2022Article
- Neural Network-Based Retinal Nerve Fiber Layer Profile Compensation for Glaucoma Diagnosis in Myopia: Model Development and Validation.JMIR medical informatics · 2021Article
- Advanced Retinal Imaging and Ocular Parameters of the Rhesus Macaque Eye.Translational vision science & technology · 2021Article
- The relationship between Subfoveal Choroidal Thickness and Hypertensive Retinopathy.Scientific reports · 2021Article
- Determining the Location of the Fovea Centralis Via En-Face SLO and Cross-Sectional OCT Imaging in Patients Without Retinal Pathology.Translational vision science & technology · 2021Article
- Location of Parapapillary Gamma Zone and Vertical Fovea Location. The Beijing Eye Study 2011.Investigative ophthalmology & visual science · 2021Article
Corrections and comments
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Authors and funding
7 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo determine the optic disc-fovea angle (defined as angle between the horizontal and the line between the optic disc center and the fovea) and to assess its relationships with ocular and systemic parameters.
methodsThe population-based cross-sectional Beijing Eye Study 2011 included 3468 individuals. A detailed ophthalmic examination was carried out. Using fundus photographs, we measured the disc-fovea angle.
resultsReadable fundus photographs were available for 6043 eyes of 3052 (88.0%) individuals with a mean age of 63.6±9.3 years (range: 50-91 years) and a mean axial length of 23.2±1.0 mm (range: 18.96-28.87 mm). Mean disc-fovea angle was 7.76 ± 3.63° (median: 7.65°; range: -6.3° to 28.9°). The mean inter-eye difference was 4.01 ± 2.94° (median: 3.49°; range: 0.00-22.3°). In multivariate analysis, larger disc-fovea angle was associated (regression coefficient r2: 0.08) with older age (P = 0.009; standardized regression coefficient beta: 0.05), thinner RNFL in the nasal superior sector (P<0.001; beta: -0.17), superior sector (P<0.001; beta: -0.10) and temporal superior sector (P<0.001; beta: -0.11) and thicker RNFL in the inferior sector (P<001; beta: 0.13), nasal inferior sector (P<001; beta: 0.13) and nasal sector (P = 0.007; beta: 0.06), higher prevalence of retinal vein occlusion (P = 0.02; beta: 0.04), and with larger cylindrical refractive error (P = 0.04; beta: 0.04).
conclusionsThe optic disc-fovea angle markedly influences the regional distribution of the RNFL thickness pattern. The disc-fovea angle may routinely be taken into account in the morphological glaucoma diagnosis and in the assessment of structure-function relationship in optic nerve diseases. Future studies may address potential associations between a larger disc-fovea angle and retinal vein occlusions and between the disc-fovea angle and the neuroretinal rim shape.
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