Evidence map›Paper›PMID 26544865›Full record

ArticlePloS one2015

Renal Interstitial Arteriosclerotic Lesions in Lupus Nephritis Patients: A Cohort Study from China.

Jing Huang, Sha-sha Han, Dan-dan Qin, Li-hua Wu, Yan Song, Feng Yu, Su-xia Wang, Gang Liu, Ming-hui Zhao

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
  2. Article
  3. Renal vascular lesions in childhood-onset lupus nephritis.Pediatric nephrology (Berlin, Germany) · 2025
    Article
  4. Article
  5. Article
  6. Lupus Vasculitis: An Overview.Biomedicines · 2021
    Review
  7. Article
  8. Article
  9. Review
  10. Article
  11. Review
  12. Observational
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Jing HuangRenal Division, Department of Medicine, Peking University First Hospital, Beijing, 100034 PR China.
Sha-sha HanRenal Division, Department of Medicine, Peking University First Hospital, Beijing, 100034 PR China.
Dan-dan QinDepartment of Nephrology, The 2nd Affiliated Hospital, Harbin Medical University, Harbin, Heilongjiang, 150000, PR China.
Li-hua WuDepartment of Nephrology, General Hospital of Ningxia Medical University, Yinchuan, Ningxia, 750004, PR China.
Yan SongDepartment of Nephrology, the First Affiliated Hospital of Chinese PLA General Hospital, 51 Fucheng Road, Beijing, 100048, PR China.
Feng YuRenal Division, Department of Medicine, Peking University First Hospital, Beijing, 100034 PR China.
Su-xia WangRenal Division, Department of Medicine, Peking University First Hospital, Beijing, 100034 PR China.
Gang LiuRenal Division, Department of Medicine, Peking University First Hospital, Beijing, 100034 PR China.
Ming-hui ZhaoRenal Division, Department of Medicine, Peking University First Hospital, Beijing, 100034 PR China.
Peking University First Hospital · CNPeking University · CNFirst Affiliated Hospital of Chinese PLA General Hospital · CNHarbin Medical University · CNNingxia Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe aim of this study was to evaluate renal arteriosclerotic lesions in patients with lupus nephritis and investigate their associations with clinical and pathological characteristics, especially cardio-vascular features.

designA retrospective cohort study.

participantsSeventy-nine patients with renal biopsy-proven lupus nephritis, diagnosed between January 2000 and June 2008 from Peking University First Hospital.

resultsIn clinico-pathological data, patients with arteriosclerosis had higher ratio of hypertension and more severe renal injury indices compared with patients with no renal vascular lesions. More importantly, patients with renal arteriosclerosis had worse cardiac structure and function under transthoracic echocardiographic examination. Patients with renal arteriosclerosis tend to have higher ratios of combined endpoints compared with those of no renal vascular lesions, although the difference didn't reach statistical meanings (P = 0.104).

conclusionRenal arteriosclerotic lesion was common and associated with vascular immune complex deposits in lupus nephritis. It might have a certain degree of association with poor outcomes and cardiovascular events, which needs further explorations.

Indexed as

AdolescentAdultAgedArteriosclerosisBeijingChildCohort StudiesFemaleHumansKidneyLupus NephritisMaleMiddle AgedPrognosisRetrospective StudiesRisk

Identifiers

PMID26544865
PMCPMC4636159
OpenAlexW2254248644

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.