Evidence map›Paper›PMID 26544668›Full record

ArticleJournal of child and adolescent psychopharmacology2015

Emotional and Nonemotional Conflict Processing in Pediatric and Adult Anxiety Disorders.

Andrea L Gold, Johanna M Jarcho, Dana K Rosen, Daniel S Pine, Monique Ernst

Open access · greenAbstract read
In one paragraph

Article in Journal of child and adolescent psychopharmacology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Andrea L GoldSection on Development and Affective Neuroscience, National Institute of Mental Health, National Institutes of Health , Bethesda, Maryland.
Johanna M JarchoSection on Development and Affective Neuroscience, National Institute of Mental Health, National Institutes of Health , Bethesda, Maryland.
Dana K RosenSection on Development and Affective Neuroscience, National Institute of Mental Health, National Institutes of Health , Bethesda, Maryland.
Daniel S PineSection on Development and Affective Neuroscience, National Institute of Mental Health, National Institutes of Health , Bethesda, Maryland.
Monique ErnstSection on Development and Affective Neuroscience, National Institute of Mental Health, National Institutes of Health , Bethesda, Maryland.
National Institutes of Health · USNational Institute of Mental Health · US

Funding

fMRI Studies Of Pediatric Mood And Anxiety DisordersZIAMH002781 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · PI PINE, DANIEL · 2009 to 2025
$41.5M
Intramural NIH HHS
6 · The paper itself

Abstract

objectivePerturbations in emotional conflict adaptation, an implicit regulatory process, have been observed in adult anxiety disorders. However, findings remain inconsistent and restricted to adults. The current study compares conflict adaptation in youth and adults, with and without anxiety disorders. We predicted conflict adaptation would be present in the healthy but not the anxious groups.

methodsIn a clinic setting, 111 participants (27 healthy youth, 22 anxious youth, 41 healthy adults, and 21 anxious adults) completed emotional and nonemotional conflict tasks. Groups did not differ (all p's >0.1) on intelligence quotient (IQ), gender, and socioeconomic status; age did not differ between healthy and anxious subjects in either age cohort. Separate four way mixed-design analyses of variance were conducted to test hypotheses regarding the influence of diagnosis, age group, and task type on accuracy (percent correct) and reaction time (RT) for conflict adaptation (incongruent trials preceded by incongruent vs. congruent trials) and conflict detection (incongruent vs. congruent trials).

resultsMeasures of conflict adaptation did not interact with diagnosis or age. There was a significant main effect of conflict adaptation across the overall sample in the expected direction for accuracy, but not RT. The well-replicated conflict detection effect also did emerge across tasks, with slower RT and lower accuracy for incongruent than for congruent trials. These effects were greater for the emotional than for nonemotional tasks. Finally, there were age differences in accuracy-based conflict detection specific to the emotional task, for which the size of the effect was larger for youth than for adults.

conclusionsThe current study of youth and adults did not replicate prior behavioral findings of failure to engage conflict adaptation in anxiety disorders. Therefore, more work is needed before widely adopting conflict adaptation paradigms as a standard neurocognitive marker for anxiety disorders.

Indexed as

Conflict, PsychologicalEmotionsAdaptation, PsychologicalAdolescentAdultAge FactorsAnxiety DisordersChildFemaleHumansMaleNeuropsychological TestsPsychomotor PerformanceReaction TimeYoung Adult

Identifiers

PMID26544668
PMCPMC4691651
OpenAlexW2104534658

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.