ReviewBioMed research international2015
Physiological and Neural Adaptations to Eccentric Exercise: Mechanisms and Considerations for Training.
Review in BioMed research international, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 52 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effect of Self-structured Foot Exercise on the Incidence of Plantar Foot Diabetic Ulcer Recurrence Post Healing at Least One Month
Effectiveness of Transcranial Direct Current Stimulation on Functionality and Pain in Individuals With Patellar Tendinopathy: Randomized Clinical Trial
Who cites it
52 citing papers in PubMed, 4 syntheses or guidelines pooled it, 152 citations in OpenAlex.
- The Effects of Advanced Resistance Training Prescription Methods on Strength, Power, Hypertrophy, and Performance Adaptations in Healthy Adults: A Systematic Review and Bayesian Network Meta-analysis.Sports medicine (Auckland, N.Z.) · 2026Pooled it
- Eccentric-Only Versus Concentric-Only Isokinetic Strength Training Effects on Maximal Voluntary Eccentric, Concentric and Isometric Contraction Strength: A Systematic Review and Meta-analysis.Sports medicine - open · 2025Pooled it
- Chronic Adaptations to Eccentric Cycling Training: A Systematic Review and Meta-Analysis.International journal of environmental research and public health · 2023Pooled it
- Pooled it
- Isokinetic eccentric vs. concentric training for functional ankle instability: a randomized controlled trial.Journal of orthopaedic surgery and research · 2025Trial
- Impact of eccentric cycling in coronary rehabilitation program: a pragmatic randomized controlled trial versus conventional rehabilitation.European journal of physical and rehabilitation medicine · 2024Trial
- Effects of Rehabilitative Exercise and Neuromuscular Electrical Stimulation on Muscle Morphology and Dynamic Balance in Individuals with Chronic Ankle Instability.Medicina (Kaunas, Lithuania) · 2024Trial
- Combined effect of graded Thera-Band and scapular stabilization exercises on shoulder adhesive capsulitis post-mastectomy.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023Trial
- Effect of eccentric-based rehabilitation on hand tremor intensity in Parkinson disease.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2020Trial
- Isoinertial Eccentric-Overload Training in Young Soccer Players: Effects on Strength, Sprint, Change of Direction, Agility and Soccer Shooting Precision.Journal of sports science & medicine · 2020Trial
- Specific Eccentric-Isokinetic Cluster Training Improves Static Strength Elements on Rings for Elite Gymnasts.International journal of environmental research and public health · 2019Trial
- Trial
- Trial
- Trial
- Comparison of lower limb muscle activities during eccentric lunge walking in three different step lengths.European journal of applied physiology · 2026Article
- The effect of eccentric exercise-induced delayed onset neck muscle soreness on force steadiness and the spatial distribution of neck extensor muscle activity.Scientific reports · 2026Article
- Electromyographic Activation of the Pectoralis Major and Triceps Brachii Muscles During Standard, Diamond, and Wide Hand Position Push-Ups.Muscles (Basel, Switzerland) · 2026Article
- Do Flywheel Exercises Provide Eccentric-Overload Training?Sports medicine - open · 2026Article
- Targeting TGF-β-driven fibrotic, epigenetic remodeling and Bax/Bcl-2 through polyphenol-exercise synergy: molecular implications for biomechanical impairment and rehabilitation in cancer.Frontiers in oncology · 2026Review
- Exercise synchronized with audible cues preserves motor unit action potential: a randomized control trial study.BMC sports science, medicine & rehabilitation · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Eccentric exercise is characterized by initial unfavorable effects such as subcellular muscle damage, pain, reduced fiber excitability, and initial muscle weakness. However, stretch combined with overload, as in eccentric contractions, is an effective stimulus for inducing physiological and neural adaptations to training. Eccentric exercise-induced adaptations include muscle hypertrophy, increased cortical activity, and changes in motor unit behavior, all of which contribute to improved muscle function. In this brief review, neuromuscular adaptations to different forms of exercise are reviewed, the positive training effects of eccentric exercise are presented, and the implications for training are considered.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.