Evidence map›Paper›PMID 26543796›Full record

ArticleCurrent developmental disorders reports2015

Neuroimaging in Tourette Syndrome: Research Highlights From 2014-2015.

Deanna J Greene, Bradley L Schlaggar, Kevin J Black

Open access · bronzeAbstract read
In one paragraph

Article in Current developmental disorders reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 3 pooled it
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 3 syntheses or guidelines pooled it, 44 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. Article
  6. Tourette syndrome.Nature reviews. Disease primers · 2026
    Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Immunological Dysfunction in Tourette Syndrome and Related Disorders.International journal of molecular sciences · 2021
    Review
  14. Review
  15. Observational
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Deanna J GreeneDepartment of Psychiatry, Washington University School of Medicine ; Department of Radiology, Washington University School of Medicine.
Bradley L SchlaggarDepartment of Psychiatry, Washington University School of Medicine ; Department of Radiology, Washington University School of Medicine ; Department of Neurology, Washington University School of Medicine ; Department of Anatomy & Neurobiology, Washington University School of Medicine ; Department of Pediatrics, Washington University School of Medicine.
Kevin J BlackDepartment of Psychiatry, Washington University School of Medicine ; Department of Radiology, Washington University School of Medicine ; Department of Neurology, Washington University School of Medicine ; Department of Anatomy & Neurobiology, Washington University School of Medicine.
Washington University in St. Louis · US

Funding

Washington University Intellectual and Developmental Disabilities Research Center-Administrative Down Syndrome SupplementU54HD087011 · NICHD · WASHINGTON UNIVERSITY · PI MOLEY, KELLE H · 2015 to 2019
$7.1M
Washington University Intellectual and Developmental Disabilities Research CenterP30HD062171 · NICHD · WASHINGTON UNIVERSITY · PI OLNEY, JOHN W · 2010 to 2014
$4.3M
PREDICTING OUTCOME IN CHILDREN WITH TIC DISORDERS USING NEUROIMAGING DATAK01MH104592 · NIMH · WASHINGTON UNIVERSITY · PI GREENE, DEANNA JACQUELYN · 2014 to 2018
$723k
PREDICTING OUTCOME IN CHILDREN WITH NEW-ONSET TICS USING NEUROIMAGING DATAR21NS091635 · NINDS · WASHINGTON UNIVERSITY · PI BLACK, KEVIN J, SCHLAGGAR, BRADLEY L · 2015 to 2016
$419k
NICHD NIH HHS P30 HD062171NICHD NIH HHS U54 HD087011NIMH NIH HHS K01 MH104592NINDS NIH HHS R21 NS091635
6 · The paper itself

Abstract

Tourette Syndrome (ts) is a developmental neuropsychiatric disorder of the central nervous system defined by the presence of chronic tics. While investigations of the underlying brain mechanisms have provided valuable information, a complete understanding of the pathophysiology of ts remains elusive. Neuroimaging methods provide remarkable tools for examining the human brain, and have been used to study brain structure and function in ts. In this article, we review ts neuroimaging studies published in 2014-2015. We highlight a number of noteworthy studies due to their innovative methods and interesting findings. Yet, we note that many of the recent studies share common concerns, specifically susceptibility to motion artifacts and modest sample sizes. Thus, we encourage future work to carefully address potential methodological confounds and to study larger samples to increase the potential for replicable results.

Indexed as

DiffusionfMRIFunctional ConnectivityMRINeuroimagingSpectroscopyTic DisordersTourette SyndromeTractography

Identifiers

PMID26543796
PMCPMC4629775
OpenAlexW2108304089

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.