Evidence map›Paper›PMID 26543537›Full record

ArticleJournal of diabetes investigation2015

Lack of predictive power of plasma lipids or lipoproteins for gestational diabetes mellitus in Japanese women.

Yuko Iimura, Masaaki Matsuura, Zemin Yao, Satoru Ito, Mutsunori Fujiwara, Michiyasu Yoshitsugu, Akito Miyauchi, Toru Hiyoshi

Open access · goldAbstract read
In one paragraph

Article in Journal of diabetes investigation, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Yuko IimuraDepartment of Diabetes and Endocrinology, Japanese Red Cross Medical Center Tokyo, Japan.
Masaaki MatsuuraDepartment of Cancer Genomics, Cancer Institute for JFCR Tokyo, Japan.
Zemin YaoDepartment of Biochemistry, Microbiology and Immunology, Ottawa Institute of Systems Biology, University of Ottawa Ottawa, ON, Canada.
Satoru ItoFujirebio Inc. Tokyo, Japan.
Mutsunori FujiwaraDepartment of Clinical Pathology, Japanese Red Cross Medical Center Tokyo, Japan.
Michiyasu YoshitsuguDepartment of Diabetes and Endocrinology, Japanese Red Cross Medical Center Tokyo, Japan.
Akito MiyauchiDepartment of Obstetrics and Gynecology, Japanese Red Cross Medical Center Tokyo, Japan.
Toru HiyoshiDepartment of Diabetes and Endocrinology, Japanese Red Cross Medical Center Tokyo, Japan.
Japanese Red Cross Medical Center · JPFujirebio (Japan) · JPThe Cancer Institute Hospital · JPUniversity of Ottawa · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

AIMS/

introductionTo determine the diagnostic potential of plasma lipids and apolipoproteins in gestational diabetes mellitus (GDM), we carried out a retrospective cohort study of 1,161 Japanese women at 20-28 weeks of gestation who underwent a glucose challenge test (GCT). MATERIALS AND

methodsA total of 1,161 Japanese women at 20-28 weeks of gestation underwent a GCT. Participants with a positive test (GCT[+]) underwent a subsequent oral glucose tolerance test. Clinical and biochemical parameters were determined and quantification of apolipoproteins (Apo), including ApoB, ApoB48, ApoA-I and ApoC-III, was carried out.

resultsThe prevalence of GCT(+; with a 130 mg/dL glucose cut-off) and GDM was 20% and 4%, respectively. There was a trend for increased triglycerides and ApoC-III in GDM(+) participants. However, the difference in plasma triglycerides, ApoC-III or ApoB48 did not reach statistical significance between GDM(+) and GDM(-) women. Values of 1-h glucose (P < 0.001) and fasting glucose (P = 0.002) were significant risk factors for GDM.

conclusionsPrediction of GDM using only the ApoC-III value is not easy, although triglycerides and ApoC-III were higher in the GDM(+) group. The present findings show no significant difference in plasma lipid levels between women diagnosed with GDM and those with normal glucose tolerance.

Indexed as

Apolipoprotein C-IIIGestational diabetes mellitusGlucose challenge test

Identifiers

PMID26543537
PMCPMC4627540
OpenAlexW2094069156

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.