Evidence map›Paper›PMID 26543495›Full record

ReviewComputational and mathematical methods in medicine2015

Perspectives in Intraoperative Diagnostics of Human Gliomas.

O Tyurikova, Y Dembitskaya, K Yashin, M Mishchenko, M Vedunova, I Medyanik, V Kazantsev

Open access · hybridAbstract readReview
In one paragraph

Review in Computational and mathematical methods in medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

O TyurikovaLobachevsky State University of Nizhni Novgorod, Institute of Biology and Biomedicine, Russia.
Y DembitskayaLobachevsky State University of Nizhni Novgorod, Institute of Biology and Biomedicine, Russia.
K YashinFederal State Budgetary Institution, "Privolzhsky Federal Research Medical Centre" of the Ministry of Health of the Russian Federation, Russia.
M MishchenkoLobachevsky State University of Nizhni Novgorod, Institute of Biology and Biomedicine, Russia.
M VedunovaLobachevsky State University of Nizhni Novgorod, Institute of Biology and Biomedicine, Russia ; Nizhny Novgorod State Medical Academy, Russia.
I MedyanikFederal State Budgetary Institution, "Privolzhsky Federal Research Medical Centre" of the Ministry of Health of the Russian Federation, Russia.
V KazantsevLobachevsky State University of Nizhni Novgorod, Institute of Biology and Biomedicine, Russia.
N. I. Lobachevsky State University of Nizhny Novgorod · RUMinistry of Health of the Russian Federation · RUPrivolzhsky Research Medical University · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Amongst large a variety of oncological diseases, malignant gliomas represent one of the most severe types of tumors. They are also the most common type of the brain tumors and account for over half of the astrocytic tumors. According to different sources, the average life expectancy of patients with various glioblastomas varies between 10 and 12 months and that of patients with anaplastic astrocytic tumors between 20 and 24 months. Therefore, studies of the physiology of transformed glial cells are critical for the development of treatment methods. Modern medical approaches offer complex procedures, including the microsurgical tumor removal, radiotherapy, and chemotherapy, supplemented with photodynamic therapy and immunotherapy. The most radical of them is surgical resection, which allows removing the largest part of the tumor, reduces the intracranial hypertension, and minimizes the degree of neurological deficit. However, complete removal of the tumor remains impossible. The main limitations are insufficient visualization of glioma boundaries, due to its infiltrative growth, and the necessity to preserve healthy tissue. This review is devoted to the description of advantages and disadvantages of modern intraoperative diagnostics of human gliomas and highlights potential perspectives for development of their treatment.

Indexed as

Brain NeoplasmsCell MovementComputational BiologyGliomaGlutamic AcidHumansImage-Guided BiopsyIntraoperative PeriodMagnetic Resonance ImagingOptical ImagingSurgery, Computer-AssistedUltrasonographyGlutamic Acid

Identifiers

PMID26543495
PMCPMC4620377
OpenAlexW1951033851

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.