ReviewAdolescent health, medicine and therapeutics2015
Development of hypertension in overweight adolescents: a review.
Review in Adolescent health, medicine and therapeutics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
27 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Adolescent and Childhood Obesity and Excess Morbidity and Mortality in Young Adulthood-a Systematic Review.Current obesity reports · 2021Pooled it
- Sex-Specific Associations of Childhood BMI Patterns with Cardiometabolic Risk: An 11-Year Korean Longitudinal Study.Children (Basel, Switzerland) · 2025Article
- Adolescent Obesity and Charlson Comorbidity Index in Young Adults.Journal of clinical medicine · 2025Article
- Obesity and hypertension in children and adolescents.Clinical hypertension · 2024Review
- Characteristics of adolescents referred for bariatric surgery in Abu Dhabi, United Arab Emirates.Frontiers in pediatrics · 2024Article
- Association Between Parental BMI and Offspring's Blood Pressure by Mediation Analysis: A Study Using Data From the Korean National Health and Nutrition Examination Survey.Journal of preventive medicine and public health = Yebang Uihakhoe chi · 2023Article
- Article
- Medical complications of obesity: heightened importance in a COVID era.International journal of emergency medicine · 2022Review
- Oxygen Supply System Management in an Overweight Adult after 12 Months in Antarctica-Study Case.International journal of environmental research and public health · 2021Article
- Elevated blood pressure-associated cardiometabolic risk factors and biomarkers in 16-23 years old students with or without metabolic abnormalities.Journal of human hypertension · 2021Article
- Hypertensive Measures In Schoolchildren: Risk Of Central Obesity And Protective Effect Of Moderate-To-Vigorous Physical Activity.Arquivos brasileiros de cardiologia · 2020Article
- A Non-Invasive Investigation into the Prevalence of Higher than Normal Blood Pressure, Hypertension and the Association between Blood Pressure and Body Weight in Male and Female Adolescents in the Polokwane Local Municipality, Limpopo-South Africa: A Cross-Sectional Study.Children (Basel, Switzerland) · 2020Article
- Article
- Family Dynamics in Sleep Health and Hypertension.Current hypertension reports · 2019Review
- Association of Adolescent Hypertension With Future End-stage Renal Disease.JAMA internal medicine · 2019Article
- Essential hypertension in children, a growing worldwide problem.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2019Review
- Cardiovascular Risk in Patients with Prehypertension and the Metabolic Syndrome.Current hypertension reports · 2018Review
- A scoping review protocol to map the evidence on interventions to prevent overweight and obesity in children.BMJ open · 2018Article
- An unfavorable body composition is common in early arthritis patients: A case control study.PloS one · 2018Article
- Slim Body Weight Is Highly Associated With Enhanced Lipoprotein Functionality, Higher HDL-C, and Large HDL Particle Size in Young Women.Frontiers in endocrinology · 2018Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The upward trend in adolescent hypertension is widely attributed to the adolescent obesity epidemic. Secular trends in adolescent prehypertension and hypertension have risen in congruence with increasing trends in the prevalence of overweight and obesity. The correlation between body mass index and blood pressure in adolescence is moderate to strong in most studies and strongest in those classified as overweight or obese. The mechanisms relating to the development of hypertension in overweight adolescents are unclear; however, a number of nonmodifiable and modifiable factors have been implicated. Importantly, certain clinical and biochemical markers in overweight adolescents are indicative of high risk for hypertension, including family history of hypertension and hyperinsulinemia. These characteristics may prove useful in stratifying overweight adolescents as high or low risk of comorbid hypertension. The treatment of overweight and obesity related hypertension in this population focuses on two key modalities: lifestyle change and pharmacotherapy. These approaches focus almost exclusively on weight reduction; however, a number of emerging strategies target hypertension more specifically. Among adolescents with overt hypertension there are also several factors that indicate higher risk of concurrent subclinical disease, persistent adult hypertension, and adult cardiovascular disease. This group may benefit substantially from more aggressive pharmacological treatments. Limitations in the literature relate to the paucity of studies reporting specific effects for the adolescent age group of overweight and obese individuals. Nonetheless, intervention for adiposity-related hypertension in adolescence may partially mitigate some of the cardiovascular risk in adulthood.
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