Evidence map›Paper›PMID 26543333›Full record

ReviewChinese journal of cancer research = Chung-kuo yen cheng yen chiu2015

Notes for developing a molecular test for the full characterization of circulating tumor cells.

Elisabetta Rossi, Antonella Facchinetti, Rita Zamarchi

Abstract readReview
In one paragraph

Review in Chinese journal of cancer research = Chung-kuo yen cheng yen chiu, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Elisabetta Rossi1 Department of Surgery, Oncology and Gastroenterology, Oncology Section, University of Padova, Padova, Italy ; 2 IOV-IRCCS, Padova, Italy.
Antonella Facchinetti1 Department of Surgery, Oncology and Gastroenterology, Oncology Section, University of Padova, Padova, Italy ; 2 IOV-IRCCS, Padova, Italy.
Rita Zamarchi1 Department of Surgery, Oncology and Gastroenterology, Oncology Section, University of Padova, Padova, Italy ; 2 IOV-IRCCS, Padova, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The proved association between the circulating tumor cell (CTC) levels and the patients' survival parameters has been growing interest to investigate the molecular profile of these neoplastic cells among which hide out precursors capable of initiating a new distant metastatic lesion. The full characterization of the tumor cells in peripheral blood of cancer patients is expected to be of help for understanding and (prospectively) for counteracting the metastatic process. The major hitch that is hampering the successful gaining of this result is the lack of a consensus onto standard operating procedures (SOPs) for performing what we generally define as the "liquid biopsy". Here we review the more recent acquisitions in the analysis of CTCs and tumor related nucleic acids, looking to the main open questions that are hampering their definitive employ in the routine clinical practice.

Indexed as

Circulating tumor cells (CTCs)liquid biopsysingle-cell analysis

Identifiers

PMID26543333
PMCPMC4626819

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.