Evidence map›Paper›PMID 26543199›Full record

ArticleMolecular biology of the cell2015

Forces, fluctuations, and self-organization in the nucleus.

Thoru Pederson, Megan C King, John F Marko

Abstract read
In one paragraph

Article in Molecular biology of the cell, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Nongenetic functions of the genome.Science (New York, N.Y.) · 2016
    Review
  6. The redundancy of the mammalian heterochromatic compartment.Current opinion in genetics & development · 2016
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Thoru PedersonProgram in Cell and Developmental Dynamics, Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, MA 01605 thoru.pederson@umassmed.edu megan.king@yale.edu john-marko@northwestern.edu.
Megan C KingDepartment of Cell Biology, Yale School of Medicine, New Haven, CT 06520 thoru.pederson@umassmed.edu megan.king@yale.edu john-marko@northwestern.edu.
John F MarkoDepartment of Molecular Biosciences and Department of Physics and Astronomy, Northwestern University, Evanston, IL 60208 thoru.pederson@umassmed.edu megan.king@yale.edu john-marko@northwestern.edu.

Funding

Tumor Environment and Metastasis (TEAM) Research ProgramP30CA060553 · NCI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Daniela E Matei · 1993 to 2026
$153.9M
Spatio-Temporal Organization of Chromatin and Information Transfer in CancerU54CA193419 · NCI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI BACKMAN, VADIM · 2015 to 2020
$10.4M
The role of nuclear architecture in adaptationDP2OD008429 · OD · YALE UNIVERSITY · PI KING, MEGAN C · 2011 to 2011
$2.5M
Activities of nucleoprotein complexes visualized in single-molecule experimentsR01GM105847 · NIGMS · NORTHWESTERN UNIVERSITY · PI MARKO, JOHN F · 2013 to 2025
$2.5M
RNA Transport Within the NucleusR01GM060551 · NIGMS · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI PEDERSON, THORU · 2002 to 2005
$1.1M
RNA PROCESSING AND RIBONUCLEOPROTEINR01GM021595 · NIGMS · WORCESTER FOUNDATION FOR BIOMEDICAL RES · PI PEDERSON, THORU · 1985 to 2001
$886k
NCI NIH HHS CA-193419NCI NIH HHS P30 CA060553NCI NIH HHS U54 CA193419NIGMS NIH HHS GM-105847NIGMS NIH HHS GM-21595NIGMS NIH HHS GM-60551NIGMS NIH HHS R01 GM060551NIGMS NIH HHS R01 GM105847NIH HHS DP2 OD008429NIH HHS DP2OD008429
6 · The paper itself

Abstract

We address several processes and domains in the nucleus wherein holding the perspective of physics either reveals a conundrum or is likely to enable progress.

Indexed as

Active Transport, Cell NucleusAnimalsBiophysical PhenomenaCell NucleusChromatinHumansHydrodynamicsStructure-Activity RelationshipChromatin

Identifiers

PMID26543199
PMCPMC4710223

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.