Trial reportAmerican heart journal2015
Lifestyle modification for resistant hypertension: The TRIUMPH randomized clinical trial.
Trial report in American heart journal, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 21 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Treating Resistant Hypertension Using Lifestyle Modification to Promote Health
Neurocognition, Lifestyle Modification, and Treatment Resistant Hypertension
Who cites it
21 citing papers in PubMed, 3 syntheses or guidelines pooled it, 48 citations in OpenAlex.
- A Systematic Review of the Role of Recreational Activities and Dietary Management in Treating Hypertension and Hyperglycaemia in Adults in Low- and Middle-Income Countries.International journal of environmental research and public health · 2026Pooled it
- Dietary Approaches to Stop Hypertension (DASH) for the primary and secondary prevention of cardiovascular diseases.The Cochrane database of systematic reviews · 2025Pooled it
- Resistant Hypertension: Detection, Evaluation, and Management: A Scientific Statement From the American Heart Association.Hypertension (Dallas, Tex. : 1979) · 2018Guideline
- Cognitive behavior therapy for insomnia for untreated hypertension with comorbid insomnia disorder: The SLEEPRIGHT clinical trial.Journal of clinical hypertension (Greenwich, Conn.) · 2024Trial
- Effects of Lifestyle Modification on Patients With Resistant Hypertension: Results of the TRIUMPH Randomized Clinical Trial.Circulation · 2021Trial
- Resistant Hypertension: Integration of Novel Agents and Interventional Approaches in Clinical Practice.Reviews in cardiovascular medicine · 2026Review
- Review
- When blood pressure refuses to budge: exploring the complexity of resistant hypertension.Frontiers in cardiovascular medicine · 2023Review
- 2022 Guidelines of the Taiwan Society of Cardiology and the Taiwan Hypertension Society for the Management of Hypertension.Acta Cardiologica Sinica · 2022Article
- Cerebrovascular Function, Vascular Risk, and Lifestyle Patterns in Resistant Hypertension.Journal of Alzheimer's disease : JAD · 2022Article
- Nonpharmacological Management of Resistant Hypertension.Current cardiology reports · 2021Review
- Nonadherence to Self-Care Practices, Antihypertensive Medications, and Associated Factors among Hypertensive Patients in a Follow-up Clinic at Asella Referral and Teaching Hospital, Ethiopia: A Cross-Sectional Study.International journal of hypertension · 2021Article
- Resistant Hypertension: Where are We Now and Where Do We Go from Here?Integrated blood pressure control · 2020Review
- Neurocognition in treatment-resistant hypertension: profile and associations with cardiovascular biomarkers.Journal of hypertension · 2019Article
- Resistant hypertension and cardiovascular disease mortality in the US: results from the National Health and Nutrition Examination Survey (NHANES).BMC nephrology · 2019Article
- Development and application of a respiratory device on blood pressure in adults with high blood pressure.Interventional medicine & applied science · 2019Article
- Missing ingredients for a lifestyle recipe to treat hypertension.Journal of thoracic disease · 2018Article
- Multidisciplinary Approach in the Treatment of Resistant Hypertension.Current hypertension reports · 2017Review
- Arterial (Aortic) Stiffness in Patients with Resistant Hypertension: from Assessment to Treatment.Current hypertension reports · 2017Review
- Effect of Modified Alkaline Supplementation on Syngenic Melanoma Growth in CB57/BL Mice.PloS one · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors at 4 institutions in 1 country.
Funding
Abstract
backgroundResistant hypertension (RH) is a growing health burden in this country affecting as many as 1 in 5 adults being treated for hypertension. Resistant hypertension is associated with increased risk of adverse cardiovascular disease (CVD) events and all-cause mortality. Strategies to reduce blood pressure (BP) in this high-risk population are a national priority.
methodsTRIUMPH is a single-site, prospective, randomized clinical trial to evaluate the efficacy of a center-based lifestyle intervention consisting of exercise training, reduced sodium and calorie Dietary Approaches to Stop Hypertension eating plan, and weight management compared to standardized education and physician advice in treating patients with RH. Patients (n = 150) will be randomized in a 2:1 ratio to receive either a 4-month supervised lifestyle intervention delivered in the setting of a cardiac rehabilitation center or to a standardized behavioral counseling session to simulate real-world medical practice. The primary end point is clinic BP; secondary end points include ambulatory BP and an array of CVD biomarkers including left ventricular hypertrophy, arterial stiffness, baroreceptor reflex sensitivity, insulin resistance, lipids, sympathetic nervous system activity, and inflammatory markers. Lifestyle habits, BP, and CVD risk factors also will be measured at 1-year follow-up.
conclusionsThe TRIUMPH randomized clinical trial (ClinicalTrials.gov NCT02342808) is designed to test the efficacy of an intensive, center-based lifestyle intervention compared to a standardized education and physician advice counseling session on BP and CVD biomarkers in patients with RH after 4 months of treatment and will determine whether lifestyle changes can be maintained for a year.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.