Evidence map›Paper›PMID 26542504›Full record

ArticleAmerican heart journal2015

Tools for Economic Analysis of Patient Management Interventions in Heart Failure Cost-Effectiveness Model: A Web-based program designed to evaluate the cost-effectiveness of disease management programs in heart failure.

Shelby D Reed, Matthew P Neilson, Matthew Gardner, Yanhong Li, Andrew H Briggs, Daniel E Polsky, Felicia L Graham, Margaret T Bowers, Sara C Paul, Bradi B Granger and 4 more

Open access · greenAbstract read
In one paragraph

Article in American heart journal, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 7 institutions in 2 countries.

Shelby D ReedDuke Clinical Research Institute, Duke University School of Medicine, Durham, NC; Department of Medicine, Duke University School of Medicine, Durham, NC. Electronic address: shelby.reed@duke.edu.
Matthew P NeilsonInstitute of Health and Wellbeing, University of Glasgow, Glasgow, United Kingdom.
Matthew GardnerDuke Clinical Research Institute, Duke University School of Medicine, Durham, NC.
Yanhong LiDuke Clinical Research Institute, Duke University School of Medicine, Durham, NC.
Andrew H BriggsInstitute of Health and Wellbeing, University of Glasgow, Glasgow, United Kingdom.
Daniel E PolskyDivision of General Internal Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA.
Felicia L GrahamDuke Clinical Research Institute, Duke University School of Medicine, Durham, NC.
Margaret T BowersDuke University School of Nursing, Durham, NC.
Sara C PaulCatawba Valley Cardiology, Conover, NC.
Bradi B GrangerDuke University School of Nursing, Durham, NC.
Kevin A SchulmanDuke Clinical Research Institute, Duke University School of Medicine, Durham, NC; Department of Medicine, Duke University School of Medicine, Durham, NC.
David J WhellanDepartment of Medicine, Jefferson Medical College, Thomas Jefferson University, Philadelphia, PA.
Barbara RiegelUniversity of Pennsylvania School of Nursing, Philadelphia, PA.
Wayne C LevyUniversity of Washington, Seattle, WA.
Duke University · USClinical Research Institute · USUniversity of Glasgow · GBUniversity of Pennsylvania · USCatawba Valley Medical Center · USThomas Jefferson University · USUniversity of Washington · US

Funding

Tools for Economic Analysis of Patient Management Interventions in Heart FailureR01NR011873 · NINR · DUKE UNIVERSITY · PI REED, SHELBY DERENE · 2009 to 2011
$1.2M
NINR NIH HHS R01 NR011873
6 · The paper itself

Abstract

backgroundHeart failure disease management programs can influence medical resource use and quality-adjusted survival. Because projecting long-term costs and survival is challenging, a consistent and valid approach to extrapolating short-term outcomes would be valuable.

methodsWe developed the Tools for Economic Analysis of Patient Management Interventions in Heart Failure Cost-Effectiveness Model, a Web-based simulation tool designed to integrate data on demographic, clinical, and laboratory characteristics; use of evidence-based medications; and costs to generate predicted outcomes. Survival projections are based on a modified Seattle Heart Failure Model. Projections of resource use and quality of life are modeled using relationships with time-varying Seattle Heart Failure Model scores. The model can be used to evaluate parallel-group and single-cohort study designs and hypothetical programs. Simulations consist of 10,000 pairs of virtual cohorts used to generate estimates of resource use, costs, survival, and incremental cost-effectiveness ratios from user inputs.

resultsThe model demonstrated acceptable internal and external validity in replicating resource use, costs, and survival estimates from 3 clinical trials. Simulations to evaluate the cost-effectiveness of heart failure disease management programs across 3 scenarios demonstrate how the model can be used to design a program in which short-term improvements in functioning and use of evidence-based treatments are sufficient to demonstrate good long-term value to the health care system.

conclusionThe Tools for Economic Analysis of Patient Management Interventions in Heart Failure Cost-Effectiveness Model provides researchers and providers with a tool for conducting long-term cost-effectiveness analyses of disease management programs in heart failure.

Indexed as

Disease ManagementInternetModels, EconomicCost-Benefit AnalysisHeart FailureHumansQuality of Life

Identifiers

PMID26542504
PMCPMC4638158
OpenAlexW2131625073

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.