Evidence map›Paper›PMID 26542271›Full record

Trial reportSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2016

Effects of a physical therapy program combined with manual lymphatic drainage on shoulder function, quality of life, lymphedema incidence, and pain in breast cancer patients with axillary web syndrome following axillary dissection.

Youngki Cho, Junghwa Do, Sunyoung Jung, Ohyun Kwon, Jae Yong Jeon

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05115799 (Effects of a Manual Therapy Program to Reduce the Evolution Time of Axillary Web Syndrome), which is not on this map. Cited by 63 papers, 10 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
63citing papers in PubMed, 10 pooled it
3.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05115799 naunknown statusnot on this mapstarted 2021, after this paper: background citation

Effects of a Manual Therapy Program to Reduce the Evolution Time of Axillary Web Syndrome

TypeinterventionalSponsorUniversity of MalagaRan2021 to 2024Enrolled46ConditionsBreast Cancer, Mastectomy, Lymphedema, ThrombiArmsManual Therapy, Physiotherapy, Kinesiology, Scar Massage, Kinesiotherapy, Physiotherapy, Health Education
3 · Its place in the literature

Who cites it

63 citing papers in PubMed, 10 syntheses or guidelines pooled it, 160 citations in OpenAlex.

  1. Pooled it
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  4. Effectiveness of physical therapy in axillary web syndrome after breast cancer: a systematic review and meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023
    Pooled it
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  7. Manual lymphatic drainage treatment for lymphedema: a systematic review of the literature.Journal of cancer survivorship : research and practice · 2021
    Pooled it
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  9. Resistance exercise and breast cancer-related lymphedema-a systematic review update and meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2020
    Pooled it
  10. Management of Axillary Web Syndrome after Breast Cancer: Evidence-Based Practice.Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia · 2017
    Pooled it
  11. Physiotherapy protocol to reduce the evolution time of axillary web syndrome in women post-breast cancer surgery: a randomized clinical trial.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
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3 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Youngki ChoDepartment of Rehabilitation Medicine, Asan Medical Center, University of Ulsan College of Medicine, 88, Olympic-Ro 43-Gil, Songpa-gu, 05505, Seoul, South Korea.
Junghwa DoDepartment of Rehabilitation Medicine, Asan Medical Center, University of Ulsan College of Medicine, 88, Olympic-Ro 43-Gil, Songpa-gu, 05505, Seoul, South Korea.
Sunyoung JungDepartment of Physical Therapy, Graduate School, Hosan University, Gyeongsan, South Korea.
Ohyun KwonDepartment of Physical Therapy, Graduate School, Yonsei University, Wonju, South Korea. kwonoy@yonsei.ac.kr.
Jae Yong JeonDepartment of Rehabilitation Medicine, Asan Medical Center, University of Ulsan College of Medicine, 88, Olympic-Ro 43-Gil, Songpa-gu, 05505, Seoul, South Korea. jyjeon71@gmail.com.
Asan Medical Center · KRHosan University · KRUniversity of Ulsan · KRYonsei University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe aim of this study was to evaluate the effects of physical therapy (PT) combined with manual lymphatic drainage (MLD) on shoulder function, pain, lymphedema, visible cords, and quality of life (QOL) in breast cancer patients with axillary web syndrome (AWS).

methodsIn this prospective, randomized trial, 41 breast cancer patients with visible and palpable cords on the arm and axilla and a numeric rating scale (NRS) pain score of >3 were randomly assigned to PT (3 times/week for 4 weeks; n = 20) and PT combined with MLD (5 times/week for 4 weeks; PTMLD; n = 21) groups. MLD was performed by a physical therapist and the patients themselves during week 1 and weeks 2-4, respectively. Arm volume, shoulder function (muscular strength; active range of motion; and disabilities of the arm, shoulder, and hand [DASH]); QOL (European Organization for Research and Treatment of Cancer Core and Breast Cancer-Specific QOL questionnaires), and pain (NRS) were assessed at baseline and after 4 weeks of treatment.

resultsQOL including functional and symptom aspects, shoulder flexor strength, DASH, and NRS scores were significantly improved in both groups after the 4-week intervention (P < 0.05). NRS score and arm volume were significantly lower in the PTMLD group than in the PT group (P < 0.05). Lymphedema was observed in the PT (n = 6), but not PTMLD, group (P < 0.05).

conclusionsPT improves shoulder function, pain, and QOL in breast cancer patients with AWS and combined with MLD decreases arm lymphedema.

Indexed as

DrainageMassagePhysical Therapy ModalitiesAdultAxillaBreast NeoplasmsFemaleHumansIncidenceLymphedemaLymph Node ExcisionMastectomyMiddle AgedPainProspective StudiesQuality of LifeAxillary web syndromeBreast neoplasmsPhysical therapy modalitiesQuality of life

Identifiers

PMID26542271
OpenAlexW2193066253

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.