Evidence map›Paper›PMID 26542160›Full record

ArticleThe European journal of health economics : HEPAC : health economics in prevention and care2016

Direct medical costs attributable to type 2 diabetes mellitus: a population-based study in Catalonia, Spain.

Manel Mata-Cases, Marc Casajuana, Josep Franch-Nadal, Aina Casellas, Conxa Castell, Irene Vinagre, Dídac Mauricio, Bonaventura Bolíbar

Open access · hybridAbstract read
In one paragraph

Article in The European journal of health economics : HEPAC : health economics in prevention and care, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed, 2 pooled it
6.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 2 syntheses or guidelines pooled it, 124 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Trial
  5. Basal Insulin Adherence in Patients with Type 2 Diabetes Mellitus in Routine Clinical Practice in Spain: Clinical and Economic Impact.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2026
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Tight and early HbAFrontiers in public health · 2025
    Article
  13. Article
  14. Disease and Economic Burden of Poor Metabolic and Weight Control in Type 2 Diabetes in Spain: A Systematic Literature Review.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2024
    Review
  15. Glial cell alterations in diabetes-induced neurodegeneration.Cellular and molecular life sciences : CMLS · 2024
    Review
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

Manel Mata-CasesPrimary Health Care Center La Mina, Institut Català de la Salut, Sant Adrià de Besòs, Spain.
Marc CasajuanaPrimary Healthcare Research Institute Jordi Gol (IDIAP Jordi Gol), Barcelona, Spain.
Josep Franch-NadalResearch Support Unit Barcelona Ciutat, Primary Healthcare Research Institute Jordi Gol (IDIAP Jordi Gol), Barcelona, Spain.
Aina CasellasPrimary Healthcare Research Institute Jordi Gol (IDIAP Jordi Gol), Barcelona, Spain.
Conxa CastellPublic Health Management Agency, Department of Health, Generalitat de Catalunya, Barcelona, Spain.
Irene VinagreDepartment of Endocrinology and Nutrition, Diabetes Unit, Hospital Clinic, University of Barcelona, Barcelona, Spain.
Dídac MauricioResearch Support Unit Barcelona Ciutat, Primary Healthcare Research Institute Jordi Gol (IDIAP Jordi Gol), Barcelona, Spain. didacmauricio@gmail.com.ORCID http://orcid.org/0000-0002-2868-0250
Bonaventura BolíbarPrimary Healthcare Research Institute Jordi Gol (IDIAP Jordi Gol), Barcelona, Spain.
Centro de Investigación Biomédica en Red Diabetes y Enfermedades Metabólicas Asociadas · ESUniversitat Autònoma de Barcelona · ESGeneralitat de Catalunya · ESInstitut Universitari d'Investigació en Atenció Primària Jordi Gol · ESUniversitat de Barcelona · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We estimated healthcare costs associated with patients with type 2 diabetes compared with non-diabetic subjects in a population-based primary care database through a retrospective analysis of economic impact during 2011, including 126,811 patients with type 2 diabetes in Catalonia, Spain. Total annual costs included primary care visits, hospitalizations, referrals, diagnostic tests, self-monitoring test strips, medication, and dialysis. For each patient, one control matched for age, gender and managing physician was randomly selected from a population database. The annual average cost per patient was €3110.1 and €1803.6 for diabetic and non-diabetic subjects, respectively (difference €1306.6; i.e., 72.4 % increased cost). The costs of hospitalizations were €1303.1 and €801.6 (62.0 % increase), and medication costs were €925.0 and €489.2 (89.1 % increase) in diabetic and non-diabetic subjects, respectively. In type 2 diabetic patients, hospitalizations and medications had the greatest impact on the overall cost (41.9 and 29.7 %, respectively), generating approximately 70 % of the difference between diabetic and non-diabetic subjects. Patients with poor glycaemic control (glycated haemoglobin >7 %; >53 mmol/mol) had average costs of €3296.5 versus €2848.5 for patients with good control. In the absence of macrovascular complications, average costs were €3008.1 for diabetic and €1612.4 for non-diabetic subjects, while its presence increased costs to €4814.6 and €3306.8, respectively. In conclusion, the estimated higher costs for type 2 diabetes patients compared with non-diabetic subjects are due mainly to hospitalizations and medications, and are higher among diabetic patients with poor glycaemic control and macrovascular complications.

Indexed as

Cost of IllnessHealth Care CostsAdultAgedAged, 80 and overAge FactorsCase-Control StudiesDatabases, FactualDiabetes Mellitus, Type 2FemaleHospitalizationHumansHypoglycemic AgentsLinear ModelsMaleMiddle AgedHypoglycemic AgentsCataloniaCostsPopulation databasePrimary careRetrospectiveSpainType 2 diabetes

Identifiers

PMID26542160
PMCPMC5047944
OpenAlexW2166055918

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.