Evidence map›Paper›PMID 26542036›Full record

ReviewMicrobiology spectrum2015

Proteus mirabilis and Urinary Tract Infections.

Jessica N Schaffer, Melanie M Pearson

Open access · greenAbstract readReview
In one paragraph

Review in Microbiology spectrum, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 191 papers.

0numbers the graph read from it
0cells of the map it votes in
191citing papers in PubMed
9.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

191 citing papers in PubMed, 371 citations in OpenAlex.

  1. Article
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  4. Review
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  9. Pangenome analysis ofAntimicrobial agents and chemotherapy · 2026
    Article
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  15. Review
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  19. Detection of OXA-23 and OXA-58 inMicrobiology spectrum · 2026
    Article
  20. Article

131 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Jessica N SchafferDepartment of Microbiology, New York University Langone Medical Center, New York, NY 10016.
Melanie M PearsonDepartment of Microbiology, New York University Langone Medical Center, New York, NY 10016.
NYU Langone Health · US

Funding

Contribution of Novel Frimbriae to Proteus Mirabilis VirulenceK22AI083743 · NIAID · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI PEARSON, MELANIE M. · 2011 to 2013
$359k
NIAID NIH HHS AI083743NIAID NIH HHS K22 AI083743
6 · The paper itself

Abstract

Proteus mirabilis is a Gram-negative bacterium and is well known for its ability to robustly swarm across surfaces in a striking bulls'-eye pattern. Clinically, this organism is most frequently a pathogen of the urinary tract, particularly in patients undergoing long-term catheterization. This review covers P. mirabilis with a focus on urinary tract infections (UTI), including disease models, vaccine development efforts, and clinical perspectives. Flagella-mediated motility, both swimming and swarming, is a central facet of this organism. The regulation of this complex process and its contribution to virulence is discussed, along with the type VI-secretion system-dependent intra-strain competition, which occurs during swarming. P. mirabilis uses a diverse set of virulence factors to access and colonize the host urinary tract, including urease and stone formation, fimbriae and other adhesins, iron and zinc acquisition, proteases and toxins, biofilm formation, and regulation of pathogenesis. While significant advances in this field have been made, challenges remain to combatting complicated UTI and deciphering P. mirabilis pathogenesis.

Indexed as

AnimalsCatheter-Related InfectionsDisease Models, AnimalHumansLocomotionProteus InfectionsProteus mirabilisUrinary Tract InfectionsVirulenceVirulence FactorsVirulence Factors

Identifiers

PMID26542036
PMCPMC4638163
OpenAlexW2412166435

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.