Evidence map›Paper›PMID 26541885›Full record

ArticleMolecular neurobiology2016

Acyl Ghrelin Improves Synapse Recovery in an In Vitro Model of Postanoxic Encephalopathy.

Irina I Stoyanova, Jeannette Hofmeijer, Michel J A M van Putten, Joost le Feber

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecular neurobiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.3field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 20 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Combined acupuncture andNeural regeneration research · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Irina I StoyanovaDepartment of Clinical Neurophysiology, Faculty of Science and Technology, University of Twente, Building Carré 3714, P.O. Box 217, 7500 AE, Enschede, The Netherlands. stoyanovai@yahoo.co.uk.
Jeannette HofmeijerDepartment of Clinical Neurophysiology, Faculty of Science and Technology, University of Twente, Building Carré 3714, P.O. Box 217, 7500 AE, Enschede, The Netherlands.
Michel J A M van PuttenDepartment of Clinical Neurophysiology, Faculty of Science and Technology, University of Twente, Building Carré 3714, P.O. Box 217, 7500 AE, Enschede, The Netherlands.
Joost le FeberDepartment of Clinical Neurophysiology, Faculty of Science and Technology, University of Twente, Building Carré 3714, P.O. Box 217, 7500 AE, Enschede, The Netherlands.
University of Twente · NLMedisch Spectrum Twente · NLRijnstate Hospital · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Comatose patients after cardiac arrest have a poor prognosis. Approximately half never awakes as a result of severe diffuse postanoxic encephalopathy. Several neuroprotective agents have been tested, however without significant effect. In the present study, we used cultured neuronal networks as a model system to study the general synaptic damage caused by temporary severe hypoxia and the possibility to restrict it by ghrelin treatment. Briefly, we applied hypoxia (pO

Indexed as

Models, BiologicalAnimalsBrain DiseasesCell SizeGhrelinHypoxiaNeuronsRats, WistarSynapsesSynaptophysinGhrelinSynaptophysinBrain hypoxiaGhrelinPostanoxic encephalopathySynapse density

Identifiers

PMID26541885
PMCPMC5085991
OpenAlexW2140335143

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.