Evidence map›Paper›PMID 26541834›Full record

ArticleCytotechnology2016

Components of chicken egg white extract smaller than 3 kDa in size promote 293T cell proliferation.

Guang-Ping Ruan, Xiang Yao, Jin-Xiang Wang, Ju-Fen Liu, Fan Shu, Zi-An Li, Rong-Qing Pang, Xing-Hua Pan

Open access · bronzeAbstract read
In one paragraph

Article in Cytotechnology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 92% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Guang-Ping RuanThe Cell Biological Therapy Center, Kunming General Hospital of Chengdu Military Command, Kunming, 650032, China. ruangp@126.com.
Xiang YaoThe Cell Biological Therapy Center, Kunming General Hospital of Chengdu Military Command, Kunming, 650032, China.
Jin-Xiang WangThe Cell Biological Therapy Center, Kunming General Hospital of Chengdu Military Command, Kunming, 650032, China.
Ju-Fen LiuThe Cell Biological Therapy Center, Kunming General Hospital of Chengdu Military Command, Kunming, 650032, China.
Fan ShuThe Cell Biological Therapy Center, Kunming General Hospital of Chengdu Military Command, Kunming, 650032, China.
Zi-An LiThe Cell Biological Therapy Center, Kunming General Hospital of Chengdu Military Command, Kunming, 650032, China.
Rong-Qing PangThe Cell Biological Therapy Center, Kunming General Hospital of Chengdu Military Command, Kunming, 650032, China.
Xing-Hua PanThe Cell Biological Therapy Center, Kunming General Hospital of Chengdu Military Command, Kunming, 650032, China. ynkmry@163.com.
Kunming General Hospital of Chengdu Military Command · CNCell Technology (China) · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We previously found that chicken egg white extract could promote cell survival and proliferation. In the present study, we further separated this extract into its components to identify those primarily responsible for promoting cell proliferation. Components of differing molecular weight were separated from chicken egg white extract by ultrafiltration and 293T cell cultures were supplemented with various concentrations. The effects on cell proliferation were subsequently determined by a CellTiter 96 Aqueous One Solution Cell Proliferation Assay kit (Promega). We demonstrate that components from chicken egg white smaller than 3 kDa in size are able to function as active ingredients promoting cellular proliferation. This discovery may identify a new and convenient additive for cell culture media to promote cell growth and proliferation.

Indexed as

Active ingredientsCell proliferationChicken egg white extractSeparation

Identifiers

PMID26541834
PMCPMC4960160
OpenAlexW2236642995

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.