Evidence map›Paper›PMID 26541780›Full record

ReviewJournal of nuclear medicine : official publication, Society of Nuclear Medicine2016

New Approaches to Molecular Imaging of Multiple Myeloma.

Ravi Vij, Kathryn J Fowler, Monica Shokeen

Open access · bronzeAbstract readReview
In one paragraph

Review in Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
5.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 49 citations in OpenAlex.

  1. CD46-Targeted Theranostics for PET and 225Ac-Radiopharmaceutical Therapy of Multiple Myeloma.Clinical cancer research : an official journal of the American Association for Cancer Research · 2024
    Article
  2. Molecular imaging of bone metastasis.Journal of bone oncology · 2023
    Review
  3. Article
  4. The prognostic significance of [EJNMMI research · 2021
    Article
  5. Article
  6. Development of [European journal of nuclear medicine and molecular imaging · 2021
    Article
  7. Article
  8. Article
  9. Article
  10. Preclinical Development of CD38-Targeted [Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2018
    Article
  11. Review
  12. Evaluating Acetate Metabolism for Imaging and Targeting in Multiple Myeloma.Clinical cancer research : an official journal of the American Association for Cancer Research · 2017
    Article
  13. Treatment response evaluation withEuropean journal of nuclear medicine and molecular imaging · 2017
    Article
  14. Article
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Ravi VijDivision of Hematology and Oncology, Washington University School of Medicine, Saint Louis, Missouri; and.
Kathryn J FowlerMallinckrodt Institute of Radiology, Washington University School of Medicine, Saint Louis, Missouri.
Monica ShokeenMallinckrodt Institute of Radiology, Washington University School of Medicine, Saint Louis, Missouri mshokeen@wustl.edu.
Mallinckrodt (United States) · USWashington University in St. Louis · US

Funding

Washington University Institute of Clinical and Translational SciencesUL1TR000448 · NCATS · WASHINGTON UNIVERSITY · PI EVANOFF, BRADLEY A · 2012 to 2016
$41.4M
RECEPTOR TARGETED MOLECULAR IMAGING OF MULTIPLE MYELOMAR01CA176221 · NCI · WASHINGTON UNIVERSITY · PI SHOKEEN, MONICA · 2013 to 2015
$946k
NCATS NIH HHS UL1 TR000448NCI NIH HHS 1R01CA176221NCI NIH HHS R01 CA176221
6 · The paper itself

Abstract

Molecular imaging plays an important role in detection and staging of hematologic malignancies. Multiple myeloma (MM) is an age-related hematologic malignancy of clonal bone marrow plasma cells characterized by destructive bone lesions and is fatal in most patients. Traditional skeletal survey and bone scans have sensitivity limitations for osteolytic lesions manifested in MM. Progressive biomedical imaging technologies such as low-dose CT, molecularly targeted PET, MRI, and the functional-anatomic hybrid versions (PET/CT and PET/MRI) provide incremental advancements in imaging MM. Imaging with PET and MRI using molecularly targeted probes is a promising precision medicine platform that might successfully address the clinical ambiguities of myeloma spectrum diseases. The intent of this focus article is to provide a concise review of the present status and promising developments on the horizon, such as the new molecular imaging biomarkers under investigation that can either complement or potentially supersede existing standards.

Indexed as

HumansMolecular ImagingMultiple MyelomaRadiographyRadionuclide Imagingmetabolic imagingmonoclonal gammopathy of undetermined significance (MGUS)multiple myeloma (MM)PET/CTPET/MRIreceptor very late antigen-4 (VLA-4)

Identifiers

PMID26541780
PMCPMC5673073
OpenAlexW2228023449

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.