ArticleBMC cancer2015
Prediction of survival prognosis after surgery in patients with symptomatic metastatic spinal cord compression from non-small cell lung cancer.
Article in BMC cancer, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 4 syntheses or guidelines pooled it, 36 citations in OpenAlex.
- Visceral Metastasis: A Prognostic Factor of Survival in Patients with Spinal Metastases.Orthopaedic surgery · 2020Pooled it
- Prognostic effect of factors involved in revised Tokuhashi score system for patients with spinal metastases: a systematic review and Meta-analysis.BMC cancer · 2018Pooled it
- Is Ambulatory Status a Prognostic Factor of Survival in Patients with Spinal Metastases? An Exploratory Meta-analysis.Orthopaedic surgery · 2018Pooled it
- Pooled it
- Review
- Does Duration of Symptoms in Metastatic Spine Disease Affect Recovery and Outcomes? A Systematic Review and Meta-Analysis.Global spine journal · 2026Review
- Radiotherapy-based multimodal treatment in advanced NSCLC with spinal infiltration: a case series of seven unfavorable patients.Discover oncology · 2026Article
- Preoperative Predictors of Survival in Patients With Spinal Metastatic Disease.International journal of spine surgery · 2023Article
- Predicting Survival in Patients Presenting With Spinal Epidural Metastases: The Limburg Spinal Metastasis Score.International journal of spine surgery · 2023Article
- Prediction of postoperative health-related quality of life among patients with metastatic spinal cord compression secondary to lung cancer.Frontiers in endocrinology · 2023Article
- Systemic considerations for the surgical treatment of spinal metastatic disease: a scoping literature review.The Lancet. Oncology · 2022Article
- Treatment Outcomes in Spinal Metastatic Disease With Indeterminate Stability.Global spine journal · 2022Article
- Comprehensive surgical treatment strategy for spinal metastases.Scientific reports · 2021Article
- The emergence of new prognostic scores in lung cancer patients with spinal metastasis: A 12-year single-center retrospective study.Journal of Cancer · 2021Article
- Impact of decompressive laminectomy on the functional outcome of patients with metastatic spinal cord compression and neurological impairment.Clinical & experimental metastasis · 2020Article
- Relationship Between Visceral Metastases and Survival in Patients with Metastasis-related Spinal Cord Compression.Orthopaedic surgery · 2019Article
- Prognostic Differences in Patients with Solitary and Multiple Spinal Metastases.Orthopaedic surgery · 2019Article
- Prognostic factors in patients with skeletal-related events at non-small-cell lung cancer diagnosis.Molecular and clinical oncology · 2017Article
- Article
- Percutaneous cementoplasty for painful osteolytic distal femur metastases: a case report.Journal of pain research · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe aim of this study was to develop a scoring system for prediction of survival prognosis after surgery in patients with symptomatic metastatic spinal cord compression (MSCC) from non-small cell lung cancer (NSCLC).
methodsWe retrospectively analyzed nine preoperative characteristics for survival in a series of 64 patients with NSCLC who were operated with posterior decompression and spine stabilization for MSCC. Characteristics significantly associated with survival on multivariate analysis were included in the scoring system. The scoring point for each significant characteristic was derived from the hazard ratios on Cox proportional hazards model. The total score for each patient was obtained by adding the scoring points of all significant characteristics.
resultsEastern Cooperative Oncology Group (ECOG) performance status, number of involved vertebrae, visceral metastases, and time developing motor deficits had significant impact on survival on multivariate analysis and were included in the scoring system. According to the prognostic scores, which ranged from 4 to 10 points, three prognostic groups were designed: 4-5 points (n = 22), 6-7 points (n = 23), and 8-10 points (n = 19). The corresponding 6-month survival rates were 95, 47 and 11%, respectively (P < 0.0001). In addition, the functional outcome was worse in the group of patients with 8-10 points compared with other two prognostic groups.
conclusionsThe new scoring system will enable physicians to identify patient with MSCC from NSCLC who may be a candidate for decompression and spine stabilization, more radical surgery, or supportive care alone. Patients with scores of 4-5, who have the most favorable survival prognosis and functional outcome, can be treated with more radical surgery in order to realize better local control of disease and prevent the occurrence of local disease. Patients with scores of 6-7 points should be surgical candidates, because survival prognosis and functional outcome are acceptable after surgery, while patients with scores of 8-10 points, who have the shortest survival time and poorest functional outcome after surgery, appear to be best treated with radiotherapy or best supportive care.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.