ReviewAllergy, asthma & immunology research2016
Exhaled NO: Determinants and Clinical Application in Children With Allergic Airway Disease.
Review in Allergy, asthma & immunology research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed, 62 citations in OpenAlex.
- Short-term exposure to stone minerals used in asphalt affect lung function and promote pulmonary inflammation among healthy adults.Scandinavian journal of work, environment & health · 2022Trial
- Breathing Out the Truth: What Fractional Exhaled Nitric Oxide Really Tells Us About Pediatric Asthma.Diagnostics (Basel, Switzerland) · 2026Review
- Recent Accomplishments in Exhaled Breath Condensate Analysis - Molecular Aspects.Current molecular medicine · 2026Review
- Association between combined allergic rhinitis and asthma syndrome in children and nitric oxide: mechanisms, clinical significance, and research progress.Frontiers in immunology · 2026Review
- Determinants of Asthma Control in Jordanian Children: The Role of Comorbidities and FeNO Levels.Children (Basel, Switzerland) · 2025Article
- The Dual Role of Nitric Oxide in Allergic Rhinitis: From the NO/cGMP Signaling Pathway to Possible New Therapeutic Targets for Organelle Damage.Journal of inflammation research · 2025Review
- Preoperative fractional exhaled nitric oxide is a risk and predictive factor of postoperative cough for early-stage non-small cell lung cancer patients: a longitudinal study.BMC pulmonary medicine · 2024Article
- Association of Body Mass Index and Exhaled Breath Nitric Oxide: A Cross-Sectional Analysis of Shahedieh Cohort Study.Tanaffos · 2024Article
- A cross-sectional analysis of medical conditions and environmental factors associated with fractional exhaled nitric oxide (FeNO) in women and children from the ISA birth cohort, Costa Rica.Environmental research · 2023Article
- Economic impact of a more extensive use of FENO testing on the Italian population with asthma.Respiratory research · 2023Article
- The Relationship of Fractional Exhaled Nitric Oxide in Patients with AECOPD.International journal of chronic obstructive pulmonary disease · 2023Article
- Can the Chinese study on the normal range of FeNO in children evaluate standardized asthma treatment efficacy in 6- to 12-year-old children?Frontiers in pediatrics · 2023Article
- Association and interaction of OBMC public health · 2022Article
- Factors Influencing the Concentration of Exhaled Nitric Oxide (FeNO) in School Children Aged 8-9-Years-Old in Krakow, with High FeNO Values ≥ 20 ppb.Medicina (Kaunas, Lithuania) · 2022Article
- Emerging Roles and Mechanisms of lncRNA FOXD3-AS1 in Human Diseases.Frontiers in oncology · 2022Review
- Relationship Between Air Pollution and the Concentration of Nitric Oxide in the Exhaled Air (FeNO) in 8-9-Year-Old School Children in Krakow.International journal of environmental research and public health · 2021Article
- Clinical application of fractional exhaled nitric oxide and nasal nitric oxide levels for the assess eosinophilic inflammation of allergic rhinitis among children.Translational pediatrics · 2021Article
- Contributions of asthma, rhinitis and IgE to exhaled nitric oxide in adolescents.ERJ open research · 2021Article
- Cough reflex sensitivity and fractional exhaled nitric oxide in children with asthma.Physiological research · 2020Article
- The Effects of Indoor Pollutants Exposure on Allergy and Lung Inflammation: An Activation State of Neutrophils and Eosinophils in Sputum.International journal of environmental research and public health · 2020Article
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 3 countries.
Funding
Abstract
Nitric oxide (NO) is endogenously released in the airways, and the fractional concentration of NO in exhaled breath (FeNO) is now recognized as a surrogate marker of eosinophilic airway inflammation that can be measured using a noninvasive technique suitable for young children. Although FeNO levels are affected by several factors, the most important clinical determinants of increased FeNO levels are atopy, asthma, and allergic rhinitis. In addition, air pollution is an environmental determinant of FeNO that may contribute to the high prevalence of allergic disease. In this review, we discuss the mechanism for airway NO production, methods for measuring FeNO, and determinants of FeNO in children, including host and environmental factors such as air pollution. We also discuss the clinical utility of FeNO in children with asthma and allergic rhinitis and further useful directions using FeNO measurement.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.