Observational studyJournal of clinical virology : the official publication of the Pan American Society for Clinical Virology2015
Characterisation of nosocomial and community-acquired influenza in a large university hospital during two consecutive influenza seasons.
Observational study in Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 52 citations in OpenAlex.
- Risk of nosocomial respiratory syncytial virus versus influenza among adult patients in acute care hospitals.Infection prevention in practice · 2025Article
- Article
- Constructing a screening model to identify patients at high risk of hospital-acquired influenza on admission to hospital.Frontiers in public health · 2025Article
- Incidence and transmission associated with respiratory viruses in an acute care facility: An observational study.Infection control and hospital epidemiology · 2024Observational
- Prediction of hospital-acquired influenza using machine learning algorithms: a comparative study.BMC infectious diseases · 2024Observational
- Influenza vaccine hesitancy among healthcare workers in a Northeastern province in Thailand: Findings of a cross-sectional survey.PloS one · 2024Article
- Comparison of 28-Day Mortality Between Hospital- and Community-Acquired Influenza Patients.Infectious diseases & clinical microbiology · 2023Article
- Real-Time Investigation of a Large Nosocomial Influenza A Outbreak Informed by Genomic Epidemiology.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2021Article
- Epidemiological and clinical characteristics of community-acquired and nosocomial influenza cases and risk factors associated with complications: A four season analysis of all adult patients admitted in a tertiary hospital.Influenza and other respiratory viruses · 2021Observational
- Description of an influenza outbreak in a French university hospital and risk factors of nosocomial influenza.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2021Observational
- Dynamics of nosocomial parainfluenza virus type 3 and influenza virus infections at a large German University Hospital between 2012 and 2019.Diagnostic microbiology and infectious disease · 2021Observational
- Risk factors for hospital-acquired influenza A and patient characteristics: a matched case-control study.BMC infectious diseases · 2020Article
- Hospital-acquired influenza in an Australian tertiary Centre 2017: a surveillance based study.BMC pulmonary medicine · 2019Article
- [Hospital-acquired pneumonia].Medizinische Klinik, Intensivmedizin und Notfallmedizin · 2018Article
- Retrospective analysis of clinical and virological parameters of influenza cases at four university hospitals in Germany, 2015.Infection · 2017Article
- Laboratory-based surveillance of hospital-acquired respiratory virus infection in a tertiary care hospital.American journal of infection control · 2017Article
- Viral Infection in the Development and Progression of Pediatric Acute Respiratory Distress Syndrome.Frontiers in pediatrics · 2016Review
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundNosocomial influenza is increasingly recognized as an important public health threat causing considerable morbidity and mortality each year. However, data on nosocomial influenza is usually collected during outbreaks only and clinical information of nosocomial influenza is sparsely available.
objectivesTo systematically analyse the distribution of nosocomial and community-acquired influenza and epidemiological characteristics in a tertiary care unit in two consecutive seasons. STUDY
designA retrospective observational study was conducted to identify and characterise cases of nosocomial and community-acquired influenza at Freiburg University hospital from 1 January 2013 to 30 April 2014. A validated multiplex RT-PCR to detect influenza virus and other respiratory pathogens was used throughout. Clinical information was retrieved from the hospital-based information system.
resultsOverall, 218 patients with laboratory-confirmed influenza were included (179 in the first, 39 patients in the second season). A rate of 20% of nosocomial influenza was observed throughout. A fatal outcome was recorded for 9% of nosocomial cases, which were mainly associated with influenza virus A(H1N1)pdm09. Nosocomial influenza occurred in all age groups, but fatalities were only observed in patients ≥18 years. Patients with nosocomial influenza were significantly older, underwent therapy for blood malignancies and immunosuppressive regimens more frequently, and received solid organ transplantation more often compared to community-acquired patients.
conclusionsDespite the different distribution of virus subtypes and epidemiological properties between both influenza seasons, the rate of nosocomial cases remained similar. Systematic detection and targeted prevention measures seem mandatory to minimize nosocomial influenza.
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