ArticlePloS one2015
Synchronization of Spontaneous Active Motility of Hair Cell Bundles.
Article in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Complex dynamics of hair bundle of auditory nervous system (II): forced oscillations related to two cases of steady state.Cognitive neurodynamics · 2022Article
- Fast adaptation of cooperative channels engenders Hopf bifurcations in auditory hair cells.Biophysical journal · 2022Article
- Dynamics of Mechanically Coupled Hair-Cell Bundles of the Inner Ear.Biophysical journal · 2021Article
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Authors and funding
3 authors.
Funding
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Abstract
Hair cells of the inner ear exhibit an active process, believed to be crucial for achieving the sensitivity of auditory and vestibular detection. One of the manifestations of the active process is the occurrence of spontaneous hair bundle oscillations in vitro. Hair bundles are coupled by overlying membranes in vivo; hence, explaining the potential role of innate bundle motility in the generation of otoacoustic emissions requires an understanding of the effects of coupling on the active bundle dynamics. We used microbeads to connect small groups of hair cell bundles, using in vitro preparations that maintain their innate oscillations. Our experiments demonstrate robust synchronization of spontaneous oscillations, with either 1:1 or multi-mode phase-locking. The frequency of synchronized oscillation was found to be near the mean of the innate frequencies of individual bundles. Coupling also led to an improved regularity of entrained oscillations, demonstrated by an increase in the quality factor.
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