ArticleNano letters2015
Unimolecular Submersible Nanomachines. Synthesis, Actuation, and Monitoring.
Article in Nano letters, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed.
- Towards helical-chirality-controlled molecular motors.Chemical science · 2026Article
- Article
- A thermodynamic perspective on enhanced enzyme diffusion.Proceedings of the National Academy of Sciences of the United States of America · 2020Article
- Controlled Diffusion of Photoswitchable Receptors by Binding Anti-electrostatic Hydrogen-Bonded Phosphate Oligomers.Journal of the American Chemical Society · 2020Article
- Molecular Nanomachines Can Destroy Tissue or Kill Multicellular Eukaryotes.ACS applied materials & interfaces · 2020Article
- Molecular Nanomachines Disrupt Bacterial Cell Wall, Increasing Sensitivity of Extensively Drug-ResistantACS nano · 2019Article
- Enhanced Diffusion of Catalytically Active Enzymes.ACS central science · 2019Review
- Simulations of microscopic propulsion of soft elastic bodies.The European physical journal. E, Soft matter · 2018Article
- Making and Operating Molecular Machines: A Multidisciplinary Challenge.ChemistryOpen · 2018Review
- Molecular machines open cell membranes.Nature · 2017Article
- Synthesis and Photostability of Unimolecular Submersible Nanomachines: Toward Single-Molecule Tracking in Solution.Organic letters · 2016Article
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
Unimolecular submersible nanomachines (USNs) bearing light-driven motors and fluorophores are synthesized. NMR experiments demonstrate that the rotation of the motor is not quenched by the fluorophore and that the motor behaves in the same manner as the corresponding motor without attached fluorophores. No photo or thermal decomposition is observed. Through careful design of control molecules with no motor and with a slow motor, we found using single molecule fluorescence correlation spectroscopy that only the molecules with fast rotating speed (MHz range) show an enhancement in diffusion by 26% when the motor is fully activated by UV light. This suggests that the USN molecules give ∼9 nm steps upon each motor actuation. A non-unidirectional rotating motor also results in a smaller, 10%, increase in diffusion. This study gives new insight into the light actuation of motorized molecules in solution.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.