Evidence map›Paper›PMID 26540050›Full record

ReviewInternational journal of molecular sciences2015

Metagenomics: A New Way to Illustrate the Crosstalk between Infectious Diseases and Host Microbiome.

Yinfeng Zhang, Cheuk-Yin Lun, Stephen Kwok-Wing Tsui

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Semen Microbiome, Male Infertility, and Reproductive Health.International journal of molecular sciences · 2025
    Review
  4. Review
  5. Article
  6. Role of Intestinal Microbes in Chronic Liver Diseases.International journal of molecular sciences · 2022
    Review
  7. Article
  8. Semen dysbiosis-just a male problem?Frontiers in cellular and infection microbiology · 2022
    Review
  9. Host-pathogen protein-nucleic acid interactions: A comprehensive review.Computational and structural biotechnology journal · 2022
    Review
  10. Article
  11. The respiratory microbiome and nontuberculous mycobacteria: an emerging concern in human health.European respiratory review : an official journal of the European Respiratory Society · 2021
    Review
  12. Lights and Shadows of Microbiota Modulation and Cardiovascular Risk in HIV Patients.International journal of environmental research and public health · 2021
    Review
  13. Large scale microbiome profiling in the cloud.Bioinformatics (Oxford, England) · 2019
    Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. The respiratory microbiome of HIV-infected individuals.Expert review of anti-infective therapy · 2016
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Yinfeng ZhangSchool of Biomedical Sciences, The Chinese University of Hong Kong, Hong Kong, China. yinfengzh@cuhk.edu.hk.
Cheuk-Yin LunSchool of Biomedical Sciences, The Chinese University of Hong Kong, Hong Kong, China. yinyinlun@yahoo.com.hk.
Stephen Kwok-Wing TsuiSchool of Biomedical Sciences, The Chinese University of Hong Kong, Hong Kong, China. kwtsui@cuhk.edu.hk.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Microbes have co-evolved with human beings for millions of years. They play a very important role in maintaining the health of the host. With the advancement in next generation sequencing technology, the microbiome profiling in the host can be obtained under different circumstances. This review focuses on the current knowledge of the alteration of complex microbial communities upon the infection of different pathogens, such as human immunodeficiency virus, hepatitis B virus, influenza virus, and Mycobacterium tuberculosis, at different body sites. It is believed that the increased understanding of the correlation between infectious disease and the alteration of the microbiome can contribute to better management of disease progression in the future. However, future studies may need to be more integrative so as to establish the exact causality of diseases by analyzing the correlation between microorganisms within the human host and the pathogenesis of infectious diseases.

Indexed as

Host-Pathogen InteractionsMetagenomicsMicrobial InteractionsMicrobiotaAcquired Immunodeficiency SyndromeAnimalsCommunicable DiseasesHepatitis BHigh-Throughput Nucleotide SequencingHIV InfectionsHumansInfluenza, HumanTuberculosisHBVHIVinfectious diseaseinfluenzametagenomicsmicrobiomenext generation sequencingtuberculosis

Identifiers

PMID26540050
PMCPMC4661816

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.