Evidence map›Paper›PMID 26539921›Full record

ReviewCurrent opinion in critical care2015

Automated/integrated real-time clinical decision support in acute kidney injury.

Stuart L Goldstein

Abstract readReview
In one paragraph

Review in Current opinion in critical care, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 25 citations in OpenAlex.

  1. Derivation and Validation of Pediatric Sepsis-Associated Acute Kidney Injury Subphenotypes With Prognostic Relevance.Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies · 2025
    Observational
  2. Article
  3. Article
  4. Implementation Strategies for Baby NINJA (Nephrotoxic Injury Negated by Just-in-Time Action) to Prevent Neonatal Medication-Induced Kidney Injury.The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG · 2023
    Article
  5. Article
  6. Article
  7. Observational
  8. Article
  9. Review
  10. Predictive Modeling of the Risk of Acute Kidney Injury in Critical Care: A Systematic Investigation of The Class Imbalance Problem.AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science · 2019
    Article
  11. Improvement of drug prescribing in acute kidney injury with a nephrotoxic drug alert system.European journal of hospital pharmacy : science and practice · 2019
    Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Stuart L GoldsteinCenter for Acute Care Nephrology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
Cincinnati Children's Hospital Medical Center · US

Funding

Pursuing Perfection in Pediatric TheraputicsU19HS021114 · AHRQ · CINCINNATI CHILDRENS HOSP MED CTR · PI LANNON, CAROLE MARIE · 2011 to 2015
$4.2M
Reduction of Nephrotoxic Medication-Associated Acute Kidney Injury in ChildrenR18HS023763 · AHRQ · CINCINNATI CHILDRENS HOSP MED CTR · PI GOLDSTEIN, STUART L · 2015 to 2017
$1.5M
AHRQ HHS 1R18HS023763-01AHRQ HHS 1U19HS021114AHRQ HHS R18 HS023763AHRQ HHS U19 HS021114
6 · The paper itself

Abstract

purpose of reviewHealth information technology advancements have resulted in recent increased sophistication of the electronic health record, whereby patient demographic, physiological, and laboratory data can be extracted real-time and integrated into clinical decision support (CDS). RECENT

findingsThe implementation of health information technology advancements into CDS in the renal realm has been focused mainly on assessment of kidney function to guide medication dosing in the setting of reduced function or to reactively detect acute kidney injury (AKI) heralded by an abrupt increase in serum creatinine. More recent work has combined risk stratification algorithms to guide proactive diagnostic or therapeutic intervention to prevent AKI or reduce its severity. SUMMARY: Early, real-time identification and notification to healthcare providers of patients at risk for, or with, acute or chronic kidney disease can drive simple interventions to reduce harm. Similarly, screening patients at risk for AKI with these platforms to alert research personnel will lead to improve study subject recruitment. However, sole reliance on electronic health record generated alerts without active healthcare team integration and assessment represents a major barrier to the realization of the potential of CDS to improve healthcare quality and outcomes.

Indexed as

Critical IllnessAcute Kidney InjuryAlgorithmsCreatinineDecision Support Systems, ClinicalEarly DiagnosisElectronic Health RecordsHumansMonitoring, PhysiologicRisk FactorsCreatinine

Identifiers

PMID26539921
PMCPMC4855037
OpenAlexW2416019293

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.