Evidence map›Paper›PMID 26539754›Full record

ReviewPain medicine (Malden, Mass.)2015

Deconstructing Chronic Low Back Pain in the Older Adult: Step by Step Evidence and Expert-Based Recommendations for Evaluation and Treatment: Part IV: Depression.

Joseph A Carley, Jordan F Karp, Angela Gentili, Zachary A Marcum, M Carrington Reid, Eric Rodriguez, Michelle I Rossi, Joseph Shega, Stephen Thielke, Debra K Weiner

Open access · bronzeAbstract readCase ReportsReview
In one paragraph

Review in Pain medicine (Malden, Mass.), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
5.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 48 citations in OpenAlex.

  1. Exercise improves quality of life, mental health and pain in people living with osteoporosis: a systematic review and meta-analysis.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2026
    Pooled it
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  6. A history of depression in patients attending a chronic pain management clinic in South Africa: A retrospective chart review.The South African journal of psychiatry : SAJP : the journal of the Society of Psychiatrists of South Africa · 2022
    Article
  7. Article
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  9. Improved Psychosocial and Functional Outcomes and Reduced Opioid Usage Following Burst Spinal Cord Stimulation.Neuromodulation : journal of the International Neuromodulation Society · 2021
    Article
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  18. Effect of depression and neuropathic pain using questionnaires on quality of life in patients with low back pain; cross-sectional retrospective study.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2016
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

Joseph A CarleyDepartments of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA.
Jordan F KarpDepartments of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA.
Angela GentiliHunter Holmes McGuire VA Medical Center, Richmond, VA, USA.
Zachary A MarcumSchool of Pharmacy, University of Washington, Seattle, WA, USA.
M Carrington ReidDivision of Geriatrics and Palliative Medicine, Weill Cornell Medical College, New York, NY, USA.
Eric RodriguezDivision of Geriatric Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Michelle I RossiDivision of Geriatric Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Joseph ShegaVITAS Healthcare, Miami, FL, USA.
Stephen ThielkeGeriatric Research, Education, and Clinical Center, Puget Sound VA Medical Center, Seattle, WA, USA.
Debra K WeinerDepartments of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA.
University of Pittsburgh · USUniversity of Washington · USVA Pittsburgh Healthcare System · USCornell University · USUniversity Health System · US

Funding

VARIABILITY, STABILITY & SMOOTHNESS OF WALKINGP30AG024827 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI JENNIFER S BRACH · 2004 to 2026
$28.6M
Pilot CoreP30AG022845 · NIA · WEILL MEDICAL COLL OF CORNELL UNIV · PI Manney Carrington Reid · 2003 to 2026
$15.2M
Pitt Integrated Clinical and Geroscience Research Training ProgramT32AG021885 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Aditi U Gurkar · 2003 to 2026
$6.7M
Optimizing Care for Older Adults with Back Pain and DepressionR01AG033575 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI KARP, JORDAN F · 2010 to 2014
$2.3M
NIA NIH HHS AG033575NIA NIH HHS P30 AG022845NIA NIH HHS P30 AG024827NIA NIH HHS R01 AG033575NIA NIH HHS T32 AG021885
6 · The paper itself

Abstract

objectiveTo present the fourth in a series of articles designed to deconstruct chronic low back pain (CLBP) in older adults. The series presents CLBP as a syndrome, a final common pathway for the expression of multiple contributors rather than a disease localized exclusively to the lumbosacral spine. Each article addresses one of twelve important contributors to pain and disability in older adults with CLBP. This article focuses on depression.

methodsThe evaluation and treatment algorithm, a table articulating the rationale for the individual algorithm components, and stepped-care drug recommendations were developed using a modified Delphi approach. The Principal Investigator, a three-member content expert panel, and a nine-member primary care panel were involved in the iterative development of these materials. The algorithm was developed keeping in mind medications and other resources available within Veterans Health Administration (VHA) facilities. As panelists were not exclusive to the VHA, the materials can be applied in both VHA and civilian settings. The illustrative clinical case was taken from one of the contributor's clinical practice.

resultsWe present an algorithm and supportive materials to help guide the care of older adults with depression, an important contributor to CLBP. The case illustrates an example of a complex clinical presentation in which depression was an important contributor to symptoms and disability in an older adult with CLBP.

conclusionsDepression is common and should be evaluated routinely in the older adult with CLBP so that appropriately targeted treatments can be planned and implemented.

Indexed as

Pain MeasurementAged, 80 and overAlgorithmsChronic PainDepressionDepressive DisorderHumansLow Back PainMaleAgedAssessmentChronic PainDepressionElderlyLow Back PainPrimary Care

Identifiers

PMID26539754
PMCPMC4821461
OpenAlexW2510892464

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.