Evidence map›Paper›PMID 26539480›Full record

SynthesisBioMed research international2015

A Decade of Progress Using Virtual Reality for Poststroke Lower Extremity Rehabilitation: Systematic Review of the Intervention Methods.

Carlos Luque-Moreno, Alejandro Ferragut-Garcías, Cleofás Rodríguez-Blanco, Alberto Marcos Heredia-Rizo, Jesús Oliva-Pascual-Vaca, Pawel Kiper, Ángel Oliva-Pascual-Vaca

Registry-linked trialAbstract readSystematic Review
In one paragraph

Synthesis in BioMed research international, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07582497 (Telerehabilitation in a Virtual Environment for Sensorimotor and Cognitive Recovery in Patients With Post-stroke Sequelae and Parkinson's Disease), which is not on this map. Cited by 37 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 7 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07582497 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Telerehabilitation in a Virtual Environment for Sensorimotor and Cognitive Recovery in Patients With Post-stroke Sequelae and Parkinson's Disease: a Pilot Study

TypeinterventionalSponsorAzienda Usl di BolognaRan2026 to 2026Enrolled60ConditionsIctus, Stroke, Parkinson DiseaseArmsVR-based Telerehabilitation with Home Kit, Standard Rehabilitation (Conventional Care)
3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 7 syntheses or guidelines pooled it.

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  5. Home-based technologies for stroke rehabilitation: A systematic review.International journal of medical informatics · 2019
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  13. Virtual Reality for Motor and Cognitive Rehabilitation.Current topics in behavioral neurosciences · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Carlos Luque-MorenoDepartment of Physical Therapy, Faculty of Nursing, Physiotherapy and Podiatry, University of Seville, C/Avicena s/n, 41009 Seville, Spain ; Motion Analysis Laboratory, "Virgen del Rocio" Hospital, Physiotherapy Area, Avenida Manuel Siurot, 41013 Seville, Spain ; Laboratory of Kinematics and Robotics, IRCCS San Camillo Hospital Foundation, Via Alberoni 70, 30126 Venice, Italy.
Alejandro Ferragut-GarcíasDepartment of Nursing and Physiotherapy, University of the Balearic Islands, Carretera de Valldemossa, km 7,5, 07122 Palma de Mallorca, Spain.
Cleofás Rodríguez-BlancoDepartment of Physical Therapy, Faculty of Nursing, Physiotherapy and Podiatry, University of Seville, C/Avicena s/n, 41009 Seville, Spain.
Alberto Marcos Heredia-RizoDepartment of Physical Therapy, Faculty of Nursing, Physiotherapy and Podiatry, University of Seville, C/Avicena s/n, 41009 Seville, Spain.
Jesús Oliva-Pascual-VacaDepartment of Physical Therapy, Francisco Maldonado University School of Osuna, Camino de los Cipreses 1, Osuna, 41640 Seville, Spain.
Pawel KiperLaboratory of Kinematics and Robotics, IRCCS San Camillo Hospital Foundation, Via Alberoni 70, 30126 Venice, Italy.
Ángel Oliva-Pascual-VacaDepartment of Physical Therapy, Faculty of Nursing, Physiotherapy and Podiatry, University of Seville, C/Avicena s/n, 41009 Seville, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo develop a systematic review of the literature, to describe the different virtual reality (VR) interventions and interactive videogames applied to the lower extremity (LE) of stroke patients, and to analyse the results according to the most frequently used outcome measures. MATERIAL AND

methodsAn electronic search of randomized trials between January 2004 and January 2014 in different databases (Medline, Cinahl, Web of Science, PEDro, and Cochrane) was carried out. Several terms (virtual reality, feedback, stroke, hemiplegia, brain injury, cerebrovascular accident, lower limb, leg, and gait) were combined, and finally 11 articles were included according to the established inclusion and exclusion criteria.

resultsThe reviewed trials showed a high heterogeneity in terms of study design and assessment tools, which makes it difficult to compare and analyze the different types of interventions. However, most of them found a significant improvement on gait speed, balance and motor function, due to VR intervention.

conclusionsAlthough evidence is limited, it suggests that VR intervention (more than 10 sessions) in stroke patients may have a positive impact on balance, and gait recovery. Better results were obtained when a multimodal approach, combining VR and conventional physiotherapy, was used. Flexible software seems to adapt better to patients' requirements, allowing more specific and individual treatments.

Indexed as

Stroke RehabilitationUser-Computer InterfaceVideo GamesHemiplegiaHumansLower ExtremityPhysical Therapy ModalitiesRandomized Controlled Trials as TopicRecovery of Function

Identifiers

PMID26539480
PMCPMC4619784

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.