Evidence map›Paper›PMID 26539450›Full record

ReviewAnnals of translational medicine2015

Patient-related medical risk factors for periprosthetic joint infection of the hip and knee.

Aleeson Eka, Antonia F Chen

Registry-linked trialAbstract readReview
In one paragraph

Review in Annals of translational medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05932823 (Airflow and Hip Prosthesis Infections), which is not on this map. Cited by 73 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
73citing papers in PubMed, 5 pooled it
10.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05932823 completednot on this map

Airflow and Hip Prosthesis Infections: A Registry Study Comparing Laminar vs. Turbulent Flow in the Danish Hip Arthroplasty Register.

Typeobservational_patient_registrySponsorUniversity Hospital Bispebjerg and FrederiksbergRan2010 to 2021Enrolled110,000ConditionsHip Prosthesis InfectionArmsLaminary airflow
3 · Its place in the literature

Who cites it

73 citing papers in PubMed, 5 syntheses or guidelines pooled it, 174 citations in OpenAlex.

  1. Pooled it
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  4. Local antibiotics in primary hip and knee arthroplasty: a systematic review and meta-analysis.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2021
    Pooled it
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  10. DACBiomedicines · 2025
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  16. AFederal practitioner : for the health care professionals of the VA, DoD, and PHS · 2025
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13 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Aleeson EkaRothman Institute, Department of Orthopaedic Surgery, Thomas Jefferson University, Philadelphia, PA 19107, USA.
Antonia F ChenRothman Institute, Department of Orthopaedic Surgery, Thomas Jefferson University, Philadelphia, PA 19107, USA.
Rothman Institute · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Despite advancements and improvements in methods for preventing infection, periprosthetic joint infection (PJI) is a significant complication following total joint arthroplasty (TJA). Prevention is the most important strategy to deal with this disabling complication, and prevention should begin with identifying patient-related risk factors. Medical risk factors, such as morbid obesity, malnutrition, hyperglycemia, uncontrolled diabetes mellitus, rheumatoid arthritis (RA), preoperative anemia, cardiovascular disorders, chronic renal failure, smoking, alcohol abuse and depression, should be evaluated and optimized prior to surgery. Treating patients to get laboratory values under a specified threshold or cessation of certain modifiable risk factors can decrease the risk of PJI. Although significant advances have been made in past decades to identify these risk factors, there remains some uncertainty regarding the risk factors predisposing TJA patients to PJI. Through a review of the current literature, this paper aims to comprehensively evaluate and provide a better understanding of known medical risk factors for PJI after TJA.

Indexed as

periprosthetic joint infection (PJA)preoperative optimizationpreventionrisk factorsTotal joint arthroplasty (TJA)

Identifiers

PMID26539450
PMCPMC4598452
OpenAlexW2231035972

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.