Evidence map›Paper›PMID 26539242›Full record

ArticleJournal of occupational medicine and toxicology (London, England)2015

Vaccination against hepatitis b virus: are Italian medical students sufficiently protected after the public vaccination programme?

Monica Lamberti, Alfredo De Rosa, Elpidio Maria Garzillo, Anna Rita Corvino, Nicola Sannolo, Stefania De Pascalis, Eliana Di Fiore, Claudia Westermann, Antonio Arnese, Di Giuseppe Gabriella and 3 more

Erratum issuedAbstract read
In one paragraph

Article in Journal of occupational medicine and toxicology (London, England), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Observational
  5. Review
  6. Observational
  7. Article
  8. Future Healthcare Workers and Hepatitis B Vaccination: A New Generation.International journal of environmental research and public health · 2021
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Observational
  18. [Human hantavirus infections].Zentralblatt fur Arbeitsmedizin, Arbeitsschutz und Ergonomie · 2018
    Review
  19. Observational
  20. Seroprotection against Vaccine-Preventable Diseases amongst Health Care Workers in a Community Hospital, Qatar.The international journal of occupational and environmental medicine · 2016
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors.

Monica Lamberti *Department of Experimental Medicine, Section of Hygiene, Occupational Medicine and Forensic Medicine, Second University of Naples, Via dei Crecchi 16, Naples, 80133 Italy.
Alfredo De Rosa *Department of Orthodontics, Second University of Naples, Naples, Italy.
Elpidio Maria GarzilloDepartment of Experimental Medicine, Section of Hygiene, Occupational Medicine and Forensic Medicine, Second University of Naples, Via dei Crecchi 16, Naples, 80133 Italy.
Anna Rita CorvinoDepartment of Experimental Medicine, Section of Hygiene, Occupational Medicine and Forensic Medicine, Second University of Naples, Via dei Crecchi 16, Naples, 80133 Italy.
Nicola SannoloDepartment of Experimental Medicine, Section of Hygiene, Occupational Medicine and Forensic Medicine, Second University of Naples, Via dei Crecchi 16, Naples, 80133 Italy.
Stefania De PascalisDepartment of Mental Health and Public Medicine, Section of Infectious Diseases, Second University of Naples, Naples, Italy.
Eliana Di FioreDepartment of Experimental Medicine, Section of Hygiene, Occupational Medicine and Forensic Medicine, Second University of Naples, Via dei Crecchi 16, Naples, 80133 Italy.
Claudia WestermannInstitute for Health Services, Research in Dermatology and Nursing, University Medical Centre Hamburg-Eppendorf, Hamburg, Germany.
Antonio ArneseDepartment of Experimental Medicine, Section of Hygiene, Occupational Medicine and Forensic Medicine, Second University of Naples, Via dei Crecchi 16, Naples, 80133 Italy.
Di Giuseppe GabriellaDepartment of Experimental Medicine, Section of Hygiene, Occupational Medicine and Forensic Medicine, Second University of Naples, Via dei Crecchi 16, Naples, 80133 Italy.
Albert NienhausInstitute for Health Services, Research in Dermatology and Nursing, University Medical Centre Hamburg-Eppendorf, Hamburg, Germany.
Antônio Paulino Ribeiro SobrinhoDepartment of Operative Dentistry, Dental School, UFMG - Universidade Federal de Minas Gerais, Belo Horizonte, MG Brazil.
Nicola CoppolaDepartment of Mental Health and Public Medicine, Section of Infectious Diseases, Second University of Naples, Naples, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe development of a vaccine against hepatitis B virus (HBV) has been a major achievement in terms of prevention of HBV infection. For the present study, we analysed the long-term immunogenicity and effectiveness of HBV vaccination among healthcare students with different working seniorities.

methodsA cross-sectional study of undergraduate and postgraduate students attending the Medical School of the Second University of Naples was conducted between September 2012 and December 2014. HBV serum markers were determined and multivariate logistic regression analysis was used to identify factors associated with the level of long-term immunogenicity.

resultsOf the 2,932 subjects evaluated, only 33 (1.1 %) declared no history of vaccination. All vaccinated subjects were HBsAg/anti-HBc negative, 459 of which had an anti-HBs titre <10 IU/L. The latter were younger, more likely to be attending a healthcare profession school (i.e., dental hygienists, nursing, paediatric nursing, radiography and midwifery) than a medical school (at either undergraduate or postgraduate level) and more likely to have been vaccinated in infancy.

conclusionThe results of this study suggest that assessment of HBV serum markers in workers potentially exposed to hospital infections is useful to identify small numbers of unvaccinated subjects or vaccinated subjects with low antibody titre, all of whom should be referred to a booster series of vaccinations.

Indexed as

Anti-HBs titreHBV infectionHBV vaccinationHealthcare students

Identifiers

PMID26539242
PMCPMC4632277

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.