Evidence map›Paper›PMID 26538871›Full record

ReviewJournal of pharmacy & bioallied sciences2015

Biomarkers in orthodontic tooth movement.

A Anand Kumar, K Saravanan, K Kohila, S Sathesh Kumar

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Journal of pharmacy & bioallied sciences, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 2 pooled it
1.7field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 2 syntheses or guidelines pooled it, 42 citations in OpenAlex.

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  16. Detection of Ostecalcin in gingival Crevicular fluid in a Group of Orthodontic Patients.Journal of International Society of Preventive & Community Dentistry
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

A Anand KumarDepartment of Orthodontics and Dentofacial Orthopedics, JKK Dental College and Hospital, Komarapalayam, Namakkal, Tamil Nadu, India.
K SaravananDepartment of Orthodontics and Dentofacial Orthopedics, JKK Dental College and Hospital, Komarapalayam, Namakkal, Tamil Nadu, India.
K KohilaDepartment of Orthodontics and Dentofacial Orthopedics, JKK Dental College and Hospital, Komarapalayam, Namakkal, Tamil Nadu, India.
S Sathesh KumarDepartment of Orthodontics and Dentofacial Orthopedics, JKK Dental College and Hospital, Komarapalayam, Namakkal, Tamil Nadu, India.
JSS Dental College and Hospital · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tooth movement by orthodontic treatment is characterized by remodeling changes in the periodontal ligament, alveolar bone, and gingiva. A reflection of these phenomenons can be found in the gingival crevicular fluid (GCF) of moving teeth, with significant elevations in the concentrations of its components like, cytokines, neurotransmitters, growth Factors, and a arachidonic acid metabolites. GCF arises at the gingival margin and can be described as a transudate or an exudate. Several studies have focused on the composition of GCF and the changes that occur during orthodontic tooth movement (OTM). GCF component analysis is a non-invasive method for studying the cellular response of the underlying periodontium. Clinically, GCF can be easily collected using platinum loops, filter paper strips, gingival washings, and micropipettes. A number of GCF biomarkers involve in bone remodeling during OTM. The data suggest that knowledge of all the biomarkers present in the GCF that can be used to mark the changes in tooth that is undergoing orthodontic treatment may be of clinical usefulness leading to proper choice of mechanical stress to improve and to shorten treatment time and avoid side effects.

Indexed as

Biomarkersgingival crevicular fluidorthodontic tooth movementperiodontiumremodeling

Identifiers

PMID26538871
PMCPMC4606613
OpenAlexW1807192274

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.