Trial reportQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2016
Relationship between depression and health-related quality of life in patients undergoing coronary artery bypass grafting: a MOTIV-CABG substudy.
Trial report in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
7 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.
- Effect of coronary artery bypass grafting on quality of life: a meta-analysis of randomized trials.European heart journal. Quality of care & clinical outcomes · 2022Pooled it
- Bypassing the blues: Insomnia in the depressed post-CABG population.Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists · 2020Trial
- Association of Mental Health Disorders and Aortic Dissection.Annals of vascular surgery · 2021Article
- Improving health-related quality of life and adherence to health-promoting behaviors among coronary artery bypass graft patients: a non-randomized controlled trial study.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2021Article
- Elevated Cardiopulmonary Complications after Revascularization in Patients with Severe Mental Health Disorders.Cardiology & vascular research (Wilmington, Del.) · 2021Article
- Prevalence of Depression in Coronary Artery Bypass Surgery: A Systematic Review and Meta-Analysis.Journal of clinical medicine · 2020Review
- Which psychological, psychophysiological, and anthropometric factors are connected with life events, depression, and quality of life in patients with cardiovascular disease.Neuropsychiatric disease and treatment · 2017Article
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
CONTEXT/
objectivesDepression is associated with higher risk of death and major adverse cardiac events among patients undergoing coronary artery bypass grafting (CABG). This study aimed to investigate the impact of preoperative depression on health-related quality of life (HRQoL) changes over the first 12 postoperative months.
methodsPatients were the participants in the MOTIV-CABG study that was a single-center, non-stratified, randomized, double-blind, parallel-group, phase 4 trial, conducted between January 2006 and February 2012 at University Hospital, Besançon, France. The effect of preoperative depression (measured using the Beck Depression Inventory, BDI) on changes in SF-36 component summary scores [mental (MCS) and physical (PCS)] over time was tested using a generalized linear model for repeated measures. The presence of depression was defined as a BDI score >3.
resultsThere were 359 patients in this study: 217 (60.4 %) had no preoperative depression, and 142 (39.6 %) had preoperative depression. During follow-up, the MCS and PCS scores increased in both groups. The improvement was of smaller magnitude in the group of patients depressed baseline as compared to those with no depression (difference in LSM = -7.45, p < 10(-3), for MCS, and -6.80, p < 10(-3), for PCS).
conclusionPreoperative depression has a negative impact on HRQoL improvement during postoperative follow-up after CABG. It seems important to detect depression before CABG to begin antidepressant therapy and improve patients' HRQoL.
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