Evidence map›Paper›PMID 26537955›Full record

ArticleQJM : monthly journal of the Association of Physicians2016

Candida growth in urine cultures: a contemporary analysis of species and antifungal susceptibility profiles.

L Toner, N Papa, S H Aliyu, H Dev, N Lawrentschuk, Samih Al-Hayek

Open access · bronzeAbstract read
In one paragraph

Article in QJM : monthly journal of the Association of Physicians, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 16 citations in OpenAlex.

  1. Species Distribution and Determinants ofMedicina (Kaunas, Lithuania) · 2026
    Article
  2. Article
  3. Article
  4. Non-Current medical mycology · 2021
    Article
  5. Review
  6. Resensitization of Fluconazole-Resistant UrinaryPolish journal of microbiology · 2020
    Article
  7. Performance of yeast-like cell counting (YLCC) using the Sysmex UF-1000i for clinical candiduria screening.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2019
    Article
  8. Determination of antimicotic susceptibility pattern ofJournal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2019
    Article
  9. Article
  10. Distribution and antifungal susceptibility ofTherapeutic advances in infectious disease
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

L TonerFrom the Department of Surgery, Urology Unit, University of Melbourne, Melbourne, Australia liam.toner@yahoo.com.
N PapaFrom the Department of Surgery, Urology Unit, University of Melbourne, Melbourne, Australia.
S H AliyuDepartment of Microbiology.
H DevDepartment of Urology, Addenbrookes' Hospital, Cambridge University, Cambridge, UK.
N LawrentschukFrom the Department of Surgery, Urology Unit, University of Melbourne, Melbourne, Australia Olivia Newton-John Cancer Research Institute, Austin Health, Melbourne, Australia Department of Surgical Oncology, Peter MacCallum Cancer Centre, Melbourne, Australia.
Samih Al-HayekDepartment of Urology, Addenbrookes' Hospital, Cambridge University, Cambridge, UK.
Melbourne Clinic · AUAddenbrooke's Hospital · GBAustin Health · AUUniversity of Cambridge · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRecent publications suggest the distribution of Candida species causing candiduria may vary geographically, which has implications for the continued efficacy of antifungal therapy and emerging resistance.

aimTo investigate the incidence of Candiduria at a university hospital in the UK. Further, to assess the distribution of species and the accompanying antifungal susceptibility profile, in order to monitor the clinical utility of current antifungal treatment guidelines for candiduria so that patients receive the best possible outcomes from the most up to date care.

designRetrospective audit.

methodsFrom 1st January 2005 to 31st October 2014, we retrospectively reviewed 37 538 positive urine cultures recorded in a computerized laboratory results database. Identification and susceptibility testing was performed using the VITEK® 2 fungal susceptibility card (bioMérieux, Marcy d'Etoile, France).

resultsIn total, 96 cultures were positive for Candida species, of which 69 (72%) were C.albicans, which translates to a prevalence of 2.6 per 1000 positive urine cultures. Candiduria was more common in younger patients, males and catheterized females. We report 94 and 73% of isolates of C.albicans and other non-C.albicans Candida species were susceptible to fluconazole. All isolates were susceptible to amphotericin B.

conclusionsOur results add weight to the evidence supporting current European and North American guidelines recommending fluconazole or amphotericin B for treatment of candiduria, if antifungal treatment is clinically indicated.

Indexed as

AdultAmphotericin BAntifungal AgentsCandidaCandidiasisDrug Resistance, FungalFluconazoleFlucytosineHumansMicrobial Sensitivity TestsSpecies SpecificityUnited KingdomUrinary Tract InfectionsAmphotericin BAntifungal AgentsFluconazoleFlucytosine

Identifiers

PMID26537955
PMCPMC4888329
OpenAlexW2215003570

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.