Evidence map›Paper›PMID 26537950›Full record

ArticleStem cell research & therapy2015

Periostin is critical for improving the therapeutic properties of adipocyte-derived stem cells.

Theresa Chow, Ian M Rogers

Open access · goldAbstract readComment
In one paragraph

Article in Stem cell research & therapy, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact, top 89% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Relationship between polycystic ovary syndrome and high periostin level.Revista da Associacao Medica Brasileira (1992) · 2024
    Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Theresa ChowWomen's and Infants' Health, Lunenfeld Tanenbaum Research Institute, Mount Sinai Hospital and University of Toronto, 60 Murray Street, Box 40, Toronto, M5T 3L9, ON, Canada.
Ian M RogersWomen's and Infants' Health, Lunenfeld Tanenbaum Research Institute, Mount Sinai Hospital and University of Toronto, 60 Murray Street, Box 40, Toronto, M5T 3L9, ON, Canada. rogers@lunenfeld.ca.
Mount Sinai Hospital · CAUniversity of Toronto · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Periostin is a matricellular protein that is reactivated during tissue damage and repair and has been shown to be a critical regulator of multiple biological pathways involved in the repair of tissue after myocardial infarction, peripheral vascular disease, and skin wounds. The tissue repair properties attributed to periostin make it an ideal candidate to enhance the therapeutic properties of donor cells such as mesenchymal stem cells from adipocyte tissue. In a recent article in Stem Cell Research & Therapy, Qin et al. demonstrated enhanced therapeutic properties of adipocyte-derived stem cells by genetically engineering them to express periostin.

Indexed as

Limb SalvageAnimalsApolipoproteins ECell AdhesionCell Adhesion MoleculesCell HypoxiaCell MovementIschemiaApolipoproteins ECell Adhesion Molecules

Identifiers

PMID26537950
PMCPMC4634790
OpenAlexW2182475562

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.