ArticleJournal of children's orthopaedics2015
AMC: amyoplasia and distal arthrogryposis.
Article in Journal of children's orthopaedics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 39 citations in OpenAlex.
- SYNE1-Related motor neuron disease-like phenotype with mild distal contractures and 24-month clinical stability: a case report.BMC neurology · 2026Article
- Arthrogryposis Multiplex Congenita: Comprehensive Review from a Neuromuscular Standpoint.Genes · 2026Review
- Transcriptional Changes Associated with Amyoplasia.International journal of molecular sciences · 2024Article
- Early Diagnosis and Management of Arthrogryposis Multiplex Congenita in a Neonate: A Case Study.Cureus · 2024Article
- Effectiveness of the Ponseti method for congenital clubfoot in patients with arthrogryposis: A systematic review and meta-analysis of observational studies.Journal of children's orthopaedics · 2024Review
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- International multidisciplinary collaboration toward an annotated definition of arthrogryposis multiplex congenita.American journal of medical genetics. Part C, Seminars in medical genetics · 2019Article
- Novel mutations in TPM2 and PIEZO2 are responsible for distal arthrogryposis (DA) 2B and mild DA in two Chinese families.BMC medical genetics · 2018Article
- Arthrogryposis multiplex congenita-an update.Journal of children's orthopaedics · 2015Article
- Development and simulation of a passive upper extremity orthosis for amyoplasia.Journal of rehabilitation and assistive technologies engineeringArticle
Corrections and comments
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Authors and funding
1 author.
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Abstract
Arthrogryposis multiplex congenita (AMC) is a heterogeneous condition defined as multiple congenital joint contractures in two or more body areas. The common pathogenesis is impaired fetal movements. Amyoplasia, the most frequent form, is a sporadically occurring condition with hypoplastic muscles and joint contractures. Distal arthrogryposis (DA) syndromes are often hereditary, and joint involvement is predominantly in the hands and feet. In a Swedish study, 131 patients with arthrogryposis were investigated. The most frequent diagnoses were amyoplasia and DA. In amyoplasia, muscle strength was found to be more important than joint range of motion (ROM) for motor function. In DA, muscle weakness was present in 44 % of investigated patients. The clinical findings were found to be highly variable between families and also within families with DA. Fetal myopathy due to sarcomeric protein dysfunction can cause DA. An early multidisciplinary team evaluation of the child with arthrogryposis for specific diagnosis and planning of treatment is recommended. Attention should be directed at the development of muscle strength with early stimulation of active movements. Immobilization should be minimized.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.