Observational studyAlzheimer's research & therapy2015
Compression or expansion of dementia in Germany? An observational study of short-term trends in incidence and death rates of dementia between 2006/07 and 2009/10 based on German health insurance data.
Observational study in Alzheimer's research & therapy, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
37 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Recent global trends in the prevalence and incidence of dementia, and survival with dementia.Alzheimer's research & therapy · 2016Pooled it
- Mortality of people with diagnosed dementia in Germany between 2016 and 2021.Alzheimer's research & therapy · 2026Article
- Getting better or worse? How trends in healthy life expectancy within working age are shaped by diverging trends among age groups.European journal of public health · 2026Article
- Nutritional status mediates the relationship between depression and mild cognitive impairment among Chinese community-dwelling older adults.Frontiers in psychiatry · 2026Article
- Ageing populations: new challenges in longevity.BMC public health · 2025Article
- Thirty-seven-year trends in the prevalence, incidence, and prognosis of dementia in a Japanese community: the Hisayama study.Alzheimer's research & therapy · 2025Article
- Secular trends in incidence, survival, and health status at diagnosis of dementia in Sweden, 2007-2022.Alzheimer's research & therapy · 2025Article
- Declining incidence but little change in years lived with dementia in two German cohorts diagnosed with dementia in 2006/2008 and 2016/2018.Alzheimer's research & therapy · 2025Article
- A multinational cohort study of trends in survival following dementia diagnosis.Communications medicine · 2025Article
- Dementia and Risks of Temperature-Related Mortality and Hospitalizations in Germany.The journals of gerontology. Series A, Biological sciences and medical sciences · 2025Article
- Dementia in Germany: epidemiology, trends and challenges.Journal of health monitoring · 2023Article
- New cases of dementia are rising in elderly populations in Wales, UK.Journal of the neurological sciences · 2023Article
- Dementia in health claims data: The influence of different case definitions on incidence and prevalence estimates.International journal of methods in psychiatric research · 2023Article
- Compression and Expansion of Morbidity—Secular Trends Among Cohorts of the Same AgeDeutsches Arzteblatt international · 2022Review
- Sex and Gender Differences in Environmental Influences on Dementia Incidence in Germany, 2014-2019: An Observational Cohort Study Based on Health Claims Data.Journal of Alzheimer's disease : JAD · 2022Observational
- N-Nitrosodimethylamine-Contaminated Valsartan and the Risk of Cancer—A Longitudinal Cohort Study Based on German Health Insurance Data.Deutsches Arzteblatt international · 2021Article
- Mortality in Dementia from 1996 to 2015: A National Registry-Based Cohort Study.Journal of Alzheimer's disease : JAD · 2021Article
- Assessing the Progression of Alzheimer's Disease in Real-World Settings in Three European Countries.Journal of Alzheimer's disease : JAD · 2021Article
- The Effect of Chinese Square Dance Exercise on Cognitive Function in Older Women With Mild Cognitive Impairment: The Mediating Effect of Mood Status and Quality of Life.Frontiers in psychiatry · 2021Article
- Effect of Square Dance Exercise on Older Women With Mild Mental Disorders.Frontiers in psychiatry · 2021Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionThere have been recent reports about a decline in dementia incidence, but only little is known about trends in the mortality of patients with dementia. Only the simultaneous analysis of both trends can inform whether the reported decline in dementia has led to a compression of dementia into higher ages.
methodsWe used health claims data from the largest public health insurer in Germany over the two time periods 2004/07 and 2007/10. Dementia was defined according to the International Classification of Disease 10th revision (ICD-10) numbers G30, G31.0, G31.82, G23.1, F00, F01, F02, F03 and F05.1 or by a prescription of cholinesterase inhibitors or memantine or both. In the two time periods, we observed 502,065 person-years of exposure and 10,881 incident dementia cases and 10,013 person-years of exposure among the newly demented and 3049 deaths. We estimated the relative risks of the two time periods applying proportional hazard models and calculated years with or without dementia using the illness-death model.
resultsDementia incidence was significantly higher in 2006/07 than in 2009/10, whereas mortality with dementia tended to be lower in the first period, albeit statistically significant among women only. Mortality without dementia tended to be higher in the first period for men and remained stable for women. Combining these trends, we found that at age 65 remaining life years with dementia were compressed by a yearly 0.4 months for men and 1.4 months for women. At the same time, remaining life years without dementia increased by a yearly 1.4 months for men and 1.1 months for women.
conclusionsThis study provides evidence that the increase in dementia-free life years went together with an absolute compression of life years with dementia. This positive trend was particularly strong among women. Results were controlled for trends in multi-morbidity and care need, suggesting that the postponement in dementia incidence is not simply caused by a delay in diagnosis.
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