Evidence map›Paper›PMID 26537547›Full record

ArticleHealth research policy and systems2015

Comparing research investment to United Kingdom institutions and published outputs for tuberculosis, HIV and malaria: a systematic analysis across 1997-2013.

Michael G Head, Joseph R Fitchett, Gemma Derrick, Fatima B Wurie, Jonathan Meldrum, Nina Kumari, Benjamin Beattie, Christopher J Counts, Rifat Atun

Open access · goldAbstract readComparative Study
In one paragraph

Article in Health research policy and systems, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
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  3. Article
  4. Article
  5. Review
  6. Article
  7. Bibliometric analysis of publications on Campylobacter: (2000-2015).Journal of health, population, and nutrition · 2016
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 7 institutions in 2 countries.

Michael G HeadFarr Institute for Health Informatics, University College London, 222 Euston Road, London, NW1 2DA, UK. m.head@ucl.ac.uk.
Joseph R FitchettHarvard T.H. Chan School of Public Health, Harvard University, Boston, USA. m.head@ucl.ac.uk.
Gemma DerrickHealth Economics Research Group, Brunel University, London, UK. m.head@ucl.ac.uk.
Fatima B WurieFarr Institute for Health Informatics, University College London, 222 Euston Road, London, NW1 2DA, UK. m.head@ucl.ac.uk.
Jonathan MeldrumFaculty of Medical Sciences, UCL Medical School, University College London, London, UK. m.head@ucl.ac.uk.
Nina KumariImperial College London, School of Medicine, London, UK. m.head@ucl.ac.uk.
Benjamin BeattieNorthumbria Specialist Emergency Care Hospital, Northumbrian Rd, Cramlington, Northumberland, UK. m.head@ucl.ac.uk.
Christopher J CountsJohns Hopkins University School of Medicine, Baltimore, USA. m.head@ucl.ac.uk.
Rifat AtunHarvard T.H. Chan School of Public Health, Harvard University, Boston, USA. m.head@ucl.ac.uk.
Harvard University · USUniversity College London · GBBrunel University of London · GBFarr Institute · GBImperial College London · GBJohns Hopkins Medicine · USNorthumbria Specialist Emergency Care Hospital · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe "Unfinished Agenda" of infectious diseases is of great importance to policymakers and research funding agencies that require ongoing research evidence on their effective management. Journal publications help effectively share and disseminate research results to inform policy and practice. We assess research investments to United Kingdom institutions in HIV, tuberculosis and malaria, and analyse these by numbers of publications and citations and by disease and type of science.

methodsInformation on infection-related research investments awarded to United Kingdom institutions across 1997-2010 were sourced from funding agencies and individually categorised by disease and type of science. Publications were sourced from the Scopus database via keyword searches and filtered to include only publications relating to human disease and containing a United Kingdom-based first and/or last author. Data were matched by disease and type of science categories. Investment (United Kingdom pounds) and publications were compared to generate an 'investment per publication' metric; similarly, an 'investment per citation' metric was also developed as a measure of the usefulness of research.

resultsTotal research investment for all three diseases was £1.4 billion, and was greatest for HIV (£651.4 million), followed by malaria (£518.7 million) and tuberculosis (£239.1 million). There were 17,271 included publications, with 9,322 for HIV, 4,451 for malaria, and 3,498 for tuberculosis. HIV publications received the most citations (254,949), followed by malaria (148,559) and tuberculosis (100,244). According to UK pound per publication, tuberculosis (£50,691) appeared the most productive for investment, compared to HIV (£61,971) and malaria (£94,483). By type of science, public health research was most productive for HIV (£27,296) and tuberculosis (£22,273), while phase I-III trials were most productive for malaria (£60,491). According to UK pound per citation, tuberculosis (£1,797) was the most productive area for investment, compared to HIV (£2,265) and malaria (£2,834). Public health research was the most productive type of science for HIV (£2,265) and tuberculosis (£1,797), whereas phase I-III trials were most productive for malaria (£1,713).

conclusionsWhen comparing total publications and citations with research investment to United Kingdom institutions, tuberculosis research appears to perform best in terms of efficiency. There were more public health-related publications and citations for HIV and tuberculosis than other types of science. These findings demonstrate the diversity of research funding and outputs, and provide new evidence to inform research investment strategies for policymakers, funders, academic institutions, and healthcare organizations.

Indexed as

HIV InfectionsMalariaPublishingResearch Support as TopicTuberculosisBiomedical ResearchHumansInvestmentsUnited Kingdom

Identifiers

PMID26537547
PMCPMC4632337
OpenAlexW2174785772

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.