ArticleBMC bioinformatics2015
CellProfiler Tracer: exploring and validating high-throughput, time-lapse microscopy image data.
Article in BMC bioinformatics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
23 citing papers in PubMed.
- Advancing in vitro cell migration studies: a review of open-source analytical platforms for cancer and wound healing research.Cell adhesion & migration · 2025Review
- Embryonic Lethality, Juvenile Growth Variation, and Adult Sterility Correlate With Phylogenetic Distance of Danionin Hybrids.Evolution & development · 2025Article
- Antibody surface mobility amplifies FcγR signaling via Arp2/3 during phagocytosis.Biophysical journal · 2024Article
- SF3A2 promotes progression and cisplatin resistance in triple-negative breast cancer via alternative splicing of MKRN1.Science advances · 2024Article
- Methods and computational tools to study eukaryotic cell migrationFrontiers in cell and developmental biology · 2024Review
- A guide to ERK dynamics, part 1: mechanisms and models.The Biochemical journal · 2023Article
- Prediction of Contaminated Areas Using Ultraviolet Fluorescence Markers for Medical Simulation: A Mobile Phone Application Approach.Bioengineering (Basel, Switzerland) · 2023Article
- Autophagy profiling in single cells with open source CellProfiler-based image analysis.Autophagy · 2023Article
- Dynamic SUMOylation of MORC2 orchestrates chromatin remodelling and DNA repair in response to DNA damage and drives chemoresistance in breast cancer.Theranostics · 2023Article
- CancerCellTracker: a brightfield time-lapse microscopy framework for cancer drug sensitivity estimation.Bioinformatics (Oxford, England) · 2022Article
- CelltrackR: An R package for fast and flexible analysis of immune cell migration data.Immunoinformatics (Amsterdam, Netherlands) · 2021Article
- Emerging machine learning approaches to phenotyping cellular motility and morphodynamics.Physical biology · 2021Review
- Calcium-vesicles perform active diffusion in the sea urchin embryo during larval biomineralization.PLoS computational biology · 2021Article
- Review
- Community standards for open cell migration data.GigaScience · 2020Article
- TAPAS: Towards Automated Processing and Analysis of multi-dimensional bioimage data.F1000Research · 2020Article
- SeeVis-3D space-time cube rendering for visualization of microfluidics image data.Bioinformatics (Oxford, England) · 2019Article
- Inferring cell state by quantitative motility analysis reveals a dynamic state system and broken detailed balance.PLoS computational biology · 2018Article
- Kinetic analyses of vasculogenesis inform mechanistic studies.American journal of physiology. Cell physiology · 2017Article
- An end-to-end software solution for the analysis of high-throughput single-cell migration data.Scientific reports · 2017Article
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
backgroundTime-lapse analysis of cellular images is an important and growing need in biology. Algorithms for cell tracking are widely available; what researchers have been missing is a single open-source software package to visualize standard tracking output (from software like CellProfiler) in a way that allows convenient assessment of track quality, especially for researchers tuning tracking parameters for high-content time-lapse experiments. This makes quality assessment and algorithm adjustment a substantial challenge, particularly when dealing with hundreds of time-lapse movies collected in a high-throughput manner.
resultsWe present CellProfiler Tracer, a free and open-source tool that complements the object tracking functionality of the CellProfiler biological image analysis package. Tracer allows multi-parametric morphological data to be visualized on object tracks, providing visualizations that have already been validated within the scientific community for time-lapse experiments, and combining them with simple graph-based measures for highlighting possible tracking artifacts.
conclusionsCellProfiler Tracer is a useful, free tool for inspection and quality control of object tracking data, available from http://www.cellprofiler.org/tracer/.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.