ArticleNeurology2015
Quality of life in patients with TIA and minor ischemic stroke.
Article in Neurology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
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Who cites it
33 citing papers in PubMed.
- Effect of Pre-Hospitalization Fall History on Physical Activity and Sedentary Behavior After the Implementation of a Behavioral Change Approach in Patients with Minor Ischemic Stroke: A Secondary Analysis of a Randomized Controlled Trial.International journal of behavioral medicine · 2024Trial
- Utility-weighted modified rankin scale scores in patients with ischemic stroke: a multicenter observational study.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026Observational
- DWI-based deep learning radiomics nomogram for predicting the impaired quality of life in patients with unruptured intracranial aneurysm developing new iatrogenic cerebral infarcts following stent placement: a multicenter cohort study.Neurosurgical review · 2025Article
- Comparison of Factors Affecting Quality of Life in Patients with Acute Ischemic Stroke Across Different Stroke Severities.Neurology and therapy · 2025Article
- DWI Positivity in Mild, Nondisabling Acute Cerebral Ischemia: Data From the PRISMS Trial.Stroke (Hoboken, N.J.) · 2025Article
- The Role of Atrial Fibrillation and Oral Anticoagulation Status in Health-Related Quality of Life 12 Months After Ischemic Stroke or TIA.Brain and behavior · 2025Article
- Enhancing patient-reported outcomes in stroke care: a path to improved well-being.Frontiers in neurology · 2025Article
- Sensor-Acquired Reachable Workspace (RWS) Correlates with Activities of Daily Living (ADL) Function in Stroke as Measured by Functional Independence Measure (FIM) Self-Care.Sensors (Basel, Switzerland) · 2024Article
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- ABCDInternal and emergency medicine · 2022Article
- Higher comorbidity burden is associated with lower self-reported quality of life after stroke.Frontiers in neurology · 2022Article
- Quantifying changes over 1 year in motor and cognitive skill after transient ischemic attack (TIA) using robotics.Scientific reports · 2021Article
- Changes in Health-Related Quality of Life After Transient Ischemic Attack.JAMA network open · 2021Observational
- Factors associated with met and unmet rehabilitation needs after stroke: A multicentre cohort study in Denmark and Norway.Journal of rehabilitation medicine · 2021Article
- Gait Measures at Admission to Inpatient Rehabilitation after Ischemic Stroke Predict 3-Month Quality of Life and Function.PM & R : the journal of injury, function, and rehabilitation · 2021Article
- The association of stroke severity with health-related quality of life in survivors of acute cerebrovascular disease and their informal caregivers during the first year post stroke: a survey study.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2020Article
- Trade-Offs in Quality-of-Life Assessment Between the Modified Rankin Scale and Neuro-QoL Measures.Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research · 2020Article
- Differential Effects of Time to Initiation of Therapy on Disability and Quality of Life in Patients With Mild and Moderate to Severe Ischemic Stroke.Archives of physical medicine and rehabilitation · 2020Observational
- Sleep-related symptoms in patients with mild stroke.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2020Observational
Corrections and comments
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Authors and funding
10 authors.
Funding
Abstract
objectiveWe investigated health-related quality of life (HRQOL) in patients with TIA and minor ischemic stroke (MIS) using Neuro-QOL, a validated, patient-reported outcome measurement system.
methodsConsecutive patients with TIA or MIS who had (1) modified Rankin Scale (mRS) score of 0 or 1 at baseline, (2) initial NIH Stroke Scale score of ≤5, (3) no acute reperfusion treatment, and (4) 3-month follow-up, were recruited. Recurrent stroke, disability by mRS and Barthel Index, and Neuro-QOL scores in 5 prespecified domains were prospectively recorded. We assessed the proportion of patients with impaired HRQOL, defined as T scores more than 0.5 SD worse than the general population average, and identified predictors of impaired HRQOL using logistic regression.
resultsAmong 332 patients who met study criteria (mean age 65.7 years, 52.4% male), 47 (14.2%) had recurrent stroke within 90 days and 41 (12.3%) were disabled (mRS >1 or Barthel Index <95) at 3 months. Any HRQOL impairment was noted in 119 patients (35.8%). In multivariate analysis, age (adjusted odds ratio [OR] 1.02, 95% confidence interval [CI] 1.01-1.04), initial NIH Stroke Scale score (adjusted OR 1.39, 95% CI 1.17-1.64), recurrent stroke (adjusted OR 2.10, 95% CI 1.06-4.13), and proxy reporting (adjusted OR 3.94, 95% CI 1.54-10.10) were independent predictors of impaired HRQOL at 3 months.
conclusionsImpairment in HRQOL is common at 3 months after MIS and TIA. Predictors of impaired HRQOL include age, index stroke severity, and recurrent stroke. Future studies should include HRQOL measures in outcome assessment, as these may be more sensitive to mild deficits than traditional disability scales.
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