Evidence map›Paper›PMID 26536254›Full record

ArticleBiophysical journal2015

Optimal Drift Correction for Superresolution Localization Microscopy with Bayesian Inference.

Ahmed Elmokadem, Ji Yu

Abstract readValidation Study
In one paragraph

Article in Biophysical journal, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Single-molecule localization microscopy as nonlinear inverse problem.Proceedings of the National Academy of Sciences of the United States of America · 2019
    Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Ahmed ElmokademCenter for Cell Analysis and Modeling, University of Connecticut Health Center, Farmington, Connecticut.
Ji YuCenter for Cell Analysis and Modeling, University of Connecticut Health Center, Farmington, Connecticut. Electronic address: jyu@uchc.edu.

Funding

Dynamics and Topology of Phosphotyrosine-SH2 Interaction NetworksU01CA154966 · NCI · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI MAYER, BRUCE J., WHITE, FOREST M · 2011 to 2015
$2.4M
Bacterial cytoskeletal structures and dynamics at single molecule levelR01GM085301 · NIGMS · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI YU, JI · 2009 to 2013
$1.4M
A novel molecular diagnostic approach to classify lung cancers and predict responRC1CA146843 · NCI · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI HAURA, ERIC B., MAYER, BRUCE J. · 2009 to 2010
$983k
NCI NIH HHS RC1 CA146843NCI NIH HHS U01CA146843NCI NIH HHS U01 CA154966NIGMS NIH HHS R01 GM085301
6 · The paper itself

Abstract

Single-molecule-localization-based superresolution microscopy requires accurate sample drift correction to achieve good results. Common approaches for drift compensation include using fiducial markers and direct drift estimation by image correlation. The former increases the experimental complexity and the latter estimates drift at a reduced temporal resolution. Here, we present, to our knowledge, a new approach for drift correction based on the Bayesian statistical framework. The technique has the advantage of being able to calculate the drifts for every image frame of the data set directly from the single-molecule coordinates. We present the theoretical foundation of the algorithm and an implementation that achieves significantly higher accuracy than image-correlation-based estimations.

Indexed as

AlgorithmsAnimalsBayes TheoremCell Line, TumorComputer SimulationFibroblastsHumansImage Processing, Computer-AssistedMiceMicroscopyModels, MolecularMonte Carlo MethodProto-Oncogene Proteins c-crkCRK protein, humanProto-Oncogene Proteins c-crk

Identifiers

PMID26536254
PMCPMC4643251

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.