Evidence map›Paper›PMID 26536253›Full record

ReviewBiophysical journal2015

Analysis and Interpretation of Superresolution Single-Particle Trajectories.

D Holcman, N Hoze, Z Schuss

Abstract readReview
In one paragraph

Review in Biophysical journal, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Physics-informed deep learning for stochastic particle dynamics estimation.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. The Decade of Super-Resolution Microscopy of the Presynapse.Frontiers in synaptic neuroscience · 2020
    Review
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

D HolcmanApplied Mathematics and Computational Biology, IBENS Ecole Normale Supérieure, Paris, France; Churchill College, Cambridge University, Cambridge, United Kingdom. Electronic address: david.holcman@ens.fr.
N HozeETH Zürich, Institute of Integrative Biology, ETH-Zentrum CHN, Universitätsstrasse 16, Zürich, Switzerland.
Z SchussDepartment of Applied Mathematics, Tel-Aviv University, Tel-Aviv, Israel.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A large number (tens of thousands) of single molecular trajectories on a cell membrane can now be collected by superresolution methods. The data contains information about the diffusive motion of molecule, proteins, or receptors and here we review methods for its recovery by statistical analysis of the data. The information includes the forces, organization of the membrane, the diffusion tensor, the long-time behavior of the trajectories, and more. To recover the long-time behavior and statistics of long trajectories, a stochastic model of their nonequilibrium motion is required. Modeling and data analysis serve extracting novel biophysical features at an unprecedented spatiotemporal resolution. The review presents data analysis, modeling, and stochastic simulations applied in particular on surface receptors evolving in neuronal cells.

Indexed as

Models, MolecularMotionData Interpretation, StatisticalDiffusionNeuronsStochastic Processes

Identifiers

PMID26536253
PMCPMC4643198

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.