ArticleThe open ophthalmology journal2015
The Association Between Primary Open Angle Glaucoma and Clustered Components of Metabolic Syndrome.
Article in The open ophthalmology journal, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.
- Cholesterol and glaucoma: a systematic review and meta-analysis.Acta ophthalmologica · 2022Pooled it
- A Blurred Vision of Health: Metabolic Syndrome as a Risk Factor for Glaucoma in a Large Taiwanese Population Study.International journal of medical sciences · 2026Article
- Pyruvate and related energetic metabolites modulate resilience against high genetic risk for glaucoma.eLife · 2025Article
- Pyruvate and Related Energetic Metabolites Modulate Resilience Against High Genetic Risk for Glaucoma.bioRxiv : the preprint server for biology · 2025Article
- Association between metabolic syndrome and the risk of glaucoma: a meta-analysis of observational studies.Diabetology & metabolic syndrome · 2024Article
- Plasma metabolite profile for primary open-angle glaucoma in three US cohorts and the UK Biobank.Nature communications · 2023Article
- The Association between Cholesterol Levels and Severity of Normal Tension Glaucoma.Molecular vision · 2023Article
- Metabolic syndrome and its components are associated with non-arteritic anterior ischaemic optic neuropathy.BMJ open ophthalmology · 2022Article
- The Impact of Systemic Health Parameters on Intraocular Pressure in the Western Region of Saudi Arabia.Cureus · 2022Article
- Risk of Glaucoma Associated with Components of Metabolic Disease in Taiwan: A Nationwide Population-Based Study.International journal of environmental research and public health · 2021Article
- CRISPR-Based Genome Editing as a New Therapeutic Tool in Retinal Diseases.Molecular biotechnology · 2021Review
- Association of Hypertriglyceridemia and Incident Glaucoma in a Rural Chinese Population: The Handan Eye Study.Translational vision science & technology · 2021Article
- White blood cell count and clustered components of metabolic syndrome: A study in western Iran.Caspian journal of internal medicine · 2021Article
- Association between hypertriglyceridemia and open angle glaucoma: A case report.Indian journal of ophthalmology · 2019Article
- The Association between Adiposity and the Risk of Glaucoma: A Meta-Analysis.Journal of ophthalmology · 2017Review
- Prevalence of Primary Open-Angle Glaucoma and its Relationship with Smoking in the Population of the Azar Cohort: A Cross-Sectional Study.Middle East African journal of ophthalmologyArticle
Corrections and comments
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Authors and funding
7 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThere is conflicting evidence whether components of metabolic syndrome (MetS) increase or decrease the risk of primary open-angle glaucoma (POAG). The aim of the present study was to determine the association between metabolic syndrome and primary open-angle glaucoma.
methodsA total of 200 participants comprising 100 controls and 100 patients with POAG documented by clinical tests and examined by an experienced ophthalmologist using standard ophthalmologic equipment were included in the study. MetS was defined and based on ATP III criteria and POAG was defined by the criteria of the International Society of Geographic and Epidemiological Ophthalmology (ISGEO). The data were entered into the SPSS software and analyzed.
resultsThe prevalence of MetS in the glaucoma group was 53% in comparison to 38% in the control group (p=0.037). MetS was associated with an increased odds ratio for an IOP higher than 21 mmHg (OR: 1.72; 95% CI 1.03-2.79; p=0.034). The mean IOP was 24.91±4.29 mmHg in the patients without MetS, and 27.23±4.81 mmHg in those with MetS (p=0.027). The mean values of CCT were 603.64±63.16 µm in MetS patients and 579.27±72.87 µm in controls (p=0.018).
conclusionData showed an increased prevalence of components of metabolic syndrome in patients with glaucoma. The mechanisms underlying these associations need to be established in future studies. Our results support the recommendation that patients with metabolic syndrome undergo regular ophthalmological exams to monitor for the onset or progression of glaucoma.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.