Evidence map›Paper›PMID 26535059›Full record

ArticleDiabetes management (London, England)

Vitamin A: a missing link in diabetes?

Steven E Trasino, Lorraine J Gudas

Open access · greenAbstract read
In one paragraph

Article in Diabetes management (London, England). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 2 pooled it
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 2 syntheses or guidelines pooled it, 44 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. Article
  6. Article
  7. Vitamin A and Its Related Diseases.Food science & nutrition · 2025
    Review
  8. Immunometabolic effects ofImmunometabolism (Cobham, Surrey) · 2024
    Review
  9. Review
  10. Article
  11. 'Oxidative stress'-A new target in the management of diabetes mellitus.Journal of family medicine and primary care · 2023
    Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Steven E TrasinoDepartment of Pharmacology, Weill Cornell Medical College, New York, NY 10065, USA.
Lorraine J GudasDepartment of Pharmacology, Weill Cornell Medical College, New York, NY 10065, USA.
Cornell University · US

Funding

CANCER PHARMACOLOGYT32CA062948 · NCI · WEILL MEDICAL COLL OF CORNELL UNIV · PI LORRAINE J GUDAS · 1994 to 2026
$12.1M
SQUAMOUS CELL CARCINOMAS - EFFECTS OF RETINOIDSR01DE010389 · NIDCR · WEILL MEDICAL COLL OF CORNELL UNIV · PI GUDAS, LORRAINE J · 1992 to 2014
$5.2M
Retinoic Acid Binding Proteins: Functional StudiesR01CA043796 · NCI · WEILL MEDICAL COLL OF CORNELL UNIV · PI GUDAS, LORRAINE J · 1987 to 2013
$5.0M
NCI NIH HHS R01 CA043796NCI NIH HHS T32 CA062948NIDCR NIH HHS R01 DE010389
6 · The paper itself

Abstract

Vitamin A has a critical role in embryonic development, immunity and the visual cycle. In recent years, evidence has demonstrated that vitamin A can also regulate metabolic pathways implicated in the pathogenesis of obesity and diabetes. This has increased interest in the possible antiobesity and antidiabetic properties of natural and synthetic vitamin A derivatives. However, whether vitamin A deficiency or aberrations in vitamin A metabolism contribute to the pathogenesis of diabetes is not known. This perspective article will review what is currently known and new data regarding the link between vitamin A and the clinical manifestations of common and atypical forms of diabetes.

Indexed as

diabetesdietary nutrientglucose metabolisminsulinisletspancreasretinoic acidretinolvitamin Aβ cells

Identifiers

PMID26535059
PMCPMC4623591
OpenAlexW2176540671

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.