ReviewDevelopment (Cambridge, England)2015
Progress and renewal in gustation: new insights into taste bud development.
Review in Development (Cambridge, England), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 86 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
86 citing papers in PubMed, 174 citations in OpenAlex.
- Converging Signaling Networks Drive Taste Bud Morphogenesis, Turnover, and Regeneration.International journal of molecular sciences · 2026Review
- Tyrosine kinase inhibitors affect sweet taste and dysregulate fate selection of specific taste bud cell subtypes via KIT inhibition.Development (Cambridge, England) · 2026Article
- Plasticity-Driven Regeneration of Circumvallate Papilla After Lgr5+ Stem Cells Loss.International journal of biological sciences · 2026Article
- Lgr5+ ductal cells of von Ebner's glands: Candidate stem cells for turnover of posterior tongue taste buds.PloS one · 2026Article
- Nutrient Sensing by Lingual G-Protein-Coupled Taste Receptors.Methods in molecular biology (Clifton, N.J.) · 2025Article
- Developing and regenerating a sense of taste.Current topics in developmental biology · 2025Review
- Real-world safety of Tepotinib: Insights from the Food and Drug Administration Adverse Event Reporting System.PloS one · 2025Article
- Exploring the link between burning mouth syndrome and human herpesvirus-6B: a narrative review on pathogenesis.Journal of the Royal Society of New Zealand · 2025Review
- Miniaturized, portable gustation interfaces for VR/AR/MR.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Single-cell transcriptomic atlas of taste papilla aging.Aging cell · 2024Article
- Deciphering Peripheral Taste Neuron Diversity: Using Genetic Identity to Bridge Taste Bud Innervation Patterns and Functional Responses.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Article
- Characterization of Antineoplastic Agents Inducing Taste and Smell Disorders Using the FAERS Database.Pharmaceuticals (Basel, Switzerland) · 2024Article
- Leveraging Dental Stem Cells for Oral Health during Pregnancy: A Concise Review.Dentistry journal · 2024Review
- Longitudinal imaging of the taste bud in vivo with two-photon laser scanning microscopy.PloS one · 2024Article
- The effect of maternal period nutritional status on oro-sensorial fat perception and taste preference in rats.Molecular and cellular biochemistry · 2023Article
- Vimentin Localization in the Zebrafish Oral Cavity: A Potential Role in Taste Buds Regeneration.International journal of molecular sciences · 2023Article
- Taste papilla cell differentiation requires the regulation of secretory protein production by ALK3-BMP signaling in the tongue mesenchyme.Development (Cambridge, England) · 2023Article
- Histological and molecular response of oral cavity tissues to Covid-19.Molecular biology reports · 2023Review
- Ascl1-expressing cell differentiation in initially developed taste buds and taste organoids.Cell and tissue research · 2023Article
26 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
The sense of taste, or gustation, is mediated by taste buds, which are housed in specialized taste papillae found in a stereotyped pattern on the surface of the tongue. Each bud, regardless of its location, is a collection of ∼100 cells that belong to at least five different functional classes, which transduce sweet, bitter, salt, sour and umami (the taste of glutamate) signals. Taste receptor cells harbor functional similarities to neurons but, like epithelial cells, are rapidly and continuously renewed throughout adult life. Here, I review recent advances in our understanding of how the pattern of taste buds is established in embryos and discuss the cellular and molecular mechanisms governing taste cell turnover. I also highlight how these findings aid our understanding of how and why many cancer therapies result in taste dysfunction.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.