Evidence map›Paper›PMID 26534788›Full record

ArticlePsychology & health2016

Medication beliefs and structural barriers to treatment adherence among people living with HIV infection.

Seth Kalichman, Moira O Kalichman, Chauncey Cherry

Abstract read
In one paragraph

Article in Psychology & health, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 2 pooled it
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Seth Kalichmana Department of Psychology , University of Connecticut , Storrs , CT , USA.
Moira O Kalichmana Department of Psychology , University of Connecticut , Storrs , CT , USA.
Chauncey Cherrya Department of Psychology , University of Connecticut , Storrs , CT , USA.

Funding

Behavioral Intervention to Enhance HIV Test/TreatR01DA033067 · NIDA · UNIVERSITY OF CONNECTICUT STORRS · PI KALICHMAN, SETH C · 2012 to 2016
$3.3M
Influence of Food Insecurity on AdherenceR01AA021471 · NIAAA · UNIVERSITY OF CONNECTICUT STORRS · PI KALICHMAN, SETH C · 2013 to 2015
$941k
NIAAA NIH HHS R01 AA021471NIAAA NIH HHS R01-AA021471NIDA NIH HHS R01 DA033067NIDA NIH HHS R01-DA033067
6 · The paper itself

Abstract

backgroundPeople living in poverty face multiple structural challenges to medication adherence including lack of transportation, inadequate housing and food insecurity. The degree to which individuals' motivations to remain adherent may overcome structural barriers has received limited attention. PURPOSE: To examine whether medication necessity and concerns beliefs predict antiretroviral therapy (ART) adherence over and above structural adherence barriers associated with poverty.

methodsPeople living with HIV in a southern US city (N = 942) completed computerised interviews, an objective measure of adherence and HIV viral suppression obtained from medical records. Hierarchical logistic regression models were constructed to examine demographic and illness characteristics, structural barriers, mental health, substance use and medication necessity and concerns beliefs as predictors of ART adherence.

resultsIn multivariable models, current drug use and medication necessity and concerns beliefs predicted treatment adherence over and above demographic, health, mental health and structural factors.

conclusionsMedication beliefs are proximal and powerful motivating factors that predict adherence. Adherence interventions should directly address medication beliefs in developing strategies to manage barriers facing people with HIV living in poverty.

Indexed as

Health Knowledge, Attitudes, PracticeHealth Services AccessibilityAdultAnti-Retroviral AgentsDrug MonitoringFemaleHIV InfectionsHumansLogistic ModelsMaleMedication AdherenceMiddle AgedMotivationMultivariate AnalysisPovertySubstance-Related DisordersAnti-Retroviral AgentsHIV-AIDSmedication adherencemedicines necessity-concerns beliefspovertystructural barriers

Identifiers

PMID26534788
PMCPMC4918083

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.