SynthesisDigestive diseases and sciences2016
Bispectral Index Versus Standard Monitoring in Sedation for Endoscopic Procedures: A Systematic Review and Meta-Analysis.
Synthesis in Digestive diseases and sciences, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Effects of EEG-guided anesthetic depth monitoring on delirium incidence across different age groups: a systematic review and meta-analysis.BMC anesthesiology · 2026Pooled it
- Pooled it
- Index of Consciousness monitoring may effectively predict and prevent circulatory stress induced by endotracheal intubation under general anesthesia: a prospective randomized controlled trial.BMC anesthesiology · 2024Trial
- Bispectral Index Monitoring During Anesthesia Promotes Early Postoperative Recovery of Cognitive Function and Reduces Acute Delirium in Elderly Patients with Colon Carcinoma: A Prospective Controlled Study using the Attention Network Test.Medical science monitor : international medical journal of experimental and clinical research · 2018Trial
- Trial
- Monitoring the Depth of Sedation During Gastrointestinal Endoscopy: A Narrative Review of Current Evidence and Clinical Recommendations.Diagnostics (Basel, Switzerland) · 2026Review
- Consensus on the Management of Anesthetic Agents During Digestive Motility Measurements and Proposal of a Standardized Protocol for Anesthesia (French Neuro Gastroenterology Group GFNG and Committee of Anesthetic French Experts).Neurogastroenterology and motility · 2026Article
- Propofol Sedation with a Target-Controlled Infusion Pump and Bispectral Index Monitoring System in Older Patients Undergoing Antegrade Balloon-Assisted Enteroscopy.Digestive diseases and sciences · 2026Article
- qCON and qNOX-Guided Sedation Monitoring During Gastrointestinal Endoscopy: A Prospective Observational Preliminary Study.Therapeutics and clinical risk management · 2026Article
- Optimizing the timing of painless gastroscope insertion: integrating advanced monitoring tools to enhance safety and efficacy: a narrative review.Frontiers in medicine · 2026Review
- Article
- Effect of bispectral index-guided anaesthesia versus standard practice on recovery after general anaesthesia in children: A systematic review and meta-analysis.Indian journal of anaesthesia · 2025Article
- Comparison of Conscious and Deep Sedation Methods in Terms of Pulmonary Complications in ERCP Procedures of Patients with Billroth II Gastrectomy: A Retrospective Study.Journal of clinical medicine · 2025Article
- Comparison of Anesthetic and Surgical Outcomes Between General Anesthesia and Dexmedetomidine-Based Sedoanalgesia in Dacryocystorhinostomy Surgery With Bispectral Index Monitoring.Anesthesiology research and practice · 2025Article
- General anesthesia and/or deep hypnotic state in propofol-based conscious sedation for endoscopy.iGIE : innovation, investigation and insights · 2024Article
- Safety and efficacy of a low-dose combination of midazolam, alfentanil, and propofol for deep sedation of elderly patients undergoing ERCP.BMC gastroenterology · 2024Article
- Advances in Analgosedation and Periprocedural Care for Gastrointestinal Endoscopy.Life (Basel, Switzerland) · 2023Review
- [Research progress on moderate and deep sedation during wound dressing change in pediatric burn patients].Zhonghua shao shang yu chuang mian xiu fu za zhi · 2023Review
- Clinical and economic value of bispectral index monitoring for adequate endoscopic sedation.Clinical endoscopy · 2022Article
- Wavelet and pain rating index for inhalation anesthesia: A randomized controlled trial.World journal of clinical cases · 2020Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundBispectral index (BIS ) monitoring has been used as an objective measurement tool for sedation depth and has been proposed as a guidance to reduce the risk of intraprocedural over-sedation. However, the results of several studies evaluating the benefits of BIS monitoring for gastrointestinal endoscopy were not consistent.
aimsThis meta-analysis aimed to assess the reduction in total consumption of administrated propofol and recovery time under BIS during gastrointestinal endoscopy.
methodsElectronic databases (MEDLINE, EMBASE, WEB of SCIENCE, and the Cochrane Central Register of Controlled Trials) were searched for articles published through March 2015. After screening, the reviewers extracted information on 11 randomized controlled trials. A total of 1039 patients (526 in BIS and 513 in non-BIS group) were included in this study.
resultsMeta-analyses showed that the total propofol consumption (the pooled standardized mean difference [SMD]: -0.15, 95% confidence interval [CI]: -0.28 to -0.01) was significantly lower in the BIS group than in the non-BIS group, although mean propofol consumption was not significantly different. Recovery time (the pooled SMD: -0.04 [95% CI -0.46 to 0.38, P = 0.85]), procedure time (the pooled SMD: 0.13 [95% CI -0.03 to 0.29, P = 0.11]), adverse events, and satisfaction-related outcomes were not significantly superior in the BIS group when compared with the non-BIS group.
conclusionsThis first meta-analysis showed that BIS monitoring appears to be an effective and safe method for avoiding unnecessary administration of propofol and for providing adequate sedation during endoscopic procedures.
Indexed as
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.