Evidence map›Paper›PMID 26531751›Full record

ReviewCurrent hypertension reports2015

Neurohumoral Integration of Cardiovascular Function by the Lamina Terminalis.

Nicole M Cancelliere, Emily A E Black, Alastair V Ferguson

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current hypertension reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Neurocardiac Axis Physiology and Clinical Applications.International journal of cardiology. Heart & vasculature · 2024
    Review
  2. Review
  3. Article
  4. Review
  5. Anatomical Organization of the Rat Subfornical Organ.Frontiers in cellular neuroscience · 2021
    Article
  6. Angiotensin type 1a receptors in the median preoptic nucleus support intermittent hypoxia-induced hypertension.American journal of physiology. Regulatory, integrative and comparative physiology · 2019
    Article
  7. Review
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Nicole M CancelliereDepartment of Biomedical and Molecular Sciences, Queen's University, Kingston, ON, K7L 3N6, Canada.
Emily A E BlackDepartment of Biomedical and Molecular Sciences, Queen's University, Kingston, ON, K7L 3N6, Canada.
Alastair V FergusonDepartment of Biomedical and Molecular Sciences, Queen's University, Kingston, ON, K7L 3N6, Canada. avf@queensu.ca.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The mechanisms involved in cardiovascular regulation, such as vascular tone, fluid volume and blood osmolarity, are quite often mediated by signals circulating in the periphery, such as angiotensin II and sodium concentration. Research has identified areas within the lamina terminalis (LT), specifically the sensory circumventricular organs (CVOs), the subfornical organ and the organum vasculosum of the lamina terminalis, as playing crucial roles detecting and integrating information derived from these circulating signals. The median preoptic nucleus (MnPO) is a third integrative structure within the LT that influences cardiovascular homeostasis, although to date, its role is not as clearly elucidated. More recent studies have demonstrated that the CVOs are not only essential in the detection of traditional cardiovascular signals but also signals primarily considered to be important in the regulation of metabolic, reproductive and inflammatory processes that have now also been implicated in cardiovascular regulation. In this review, we highlight the critical roles played by the LT in the detection and integration of circulating signals that provide critical feedback control information contributing to cardiovascular regulation.

Indexed as

Cardiovascular Physiological PhenomenaAnimalsHomeostasisHumansHypertensionHypothalamusSodiumSodiumCardiovascular regulationCircumventricular organsLamina terminalisOrganum vasculosum of the lamina terminalisSignal integrationSubfornical organ

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.