Evidence map›Paper›PMID 26531680›Full record

ArticleScientific reports2015

Differential regulation of receptivity in two uterine horns of a recipient mouse following asynchronous embryo transfer.

Shi-Jie Li, Tong-Song Wang, Fu-Niu Qin, Zhu Huang, Xiao-Huan Liang, Fei Gao, Zhuo Song, Zeng-Ming Yang

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Delayed Implantation Induced by Letrozole in Mice.Reproductive sciences (Thousand Oaks, Calif.) · 2022
    Article
  4. Article
  5. Article
  6. Endometrial autophagy is essential for embryo implantation during early pregnancy.Journal of molecular medicine (Berlin, Germany) · 2020
    Article
  7. Effects of Intrauterine Air Bubbles on Embryonic Development in Mice.Journal of the American Association for Laboratory Animal Science : JAALAS · 2019
    Article
  8. Review
  9. Article
  10. Review
  11. Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

Shi-Jie LiColleage of Veterinary Medicine, South China Agricultural University, Guangzhou, China.
Tong-Song WangSchool of Science, Shantou University, Shantou, China.
Fu-Niu QinSchool of Life Science, Xiamen University, Xiamen, China.
Zhu HuangCollege of Life Science, Anqing Normal University, Anqing, China.
Xiao-Huan LiangColleage of Veterinary Medicine, South China Agricultural University, Guangzhou, China.
Fei GaoSchool of Science, Shantou University, Shantou, China.
Zhuo SongColleage of Veterinary Medicine, South China Agricultural University, Guangzhou, China.
Zeng-Ming YangColleage of Veterinary Medicine, South China Agricultural University, Guangzhou, China.
South China Agricultural University · CNShantou University · CNAnqing Normal University · CNNortheast Agricultural University · CNXiamen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Receptivity is a limited time in which uterine endometrium can establish a successful dialogue with blastocyst. This study was to investigate the effect of asynchronous embryo transfer on uterine receptivity in mice. Embryos under different stages were transferred into two oviduct sides of a recipient mouse on day 1 of pseudopregnancy. Our results showed the asynchronously transferred embryos can implant in all groups. Compared to zygote-transfer group, the length of implanted embryos is longer in 8-cell embryo- or blastocyst-transfer group. The levels of Snail and COX-2 immunostaining in blastocyst-transfer group are significantly stronger than that in zygote-transfer group. Embryos in blastocyst-transfer group migrate faster than that in zygote-transfer group within uterus. Blastocysts are in a state of developmental delay after they are transferred into oviducts, and they are reactivated and implanted rapidly in uterus. The developmental rate to newborn in zygote-transfer group is obviously higher than that in blastocyst-transfer group, suggesting that a delay in embryo development and implantation will lead to a decrease of litter size. These results indicated that the window of implantation is differentially regulated in two uterine horns of a recipient by embryos at different stages.

Indexed as

AnimalsBlastocystCyclooxygenase 2Embryo ImplantationEmbryonic DevelopmentEmbryo TransferEndometriumFemaleMaleMicePseudopregnancySnail Family Transcription FactorsTranscription FactorsZygoteCyclooxygenase 2Ptgs2 protein, mouseSnail Family Transcription FactorsTranscription Factors

Identifiers

PMID26531680
PMCPMC4632121
OpenAlexW2412403157

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.