Evidence map›Paper›PMID 26530404›Full record

ReviewCNS spectrums2015

Neurobiological features of binge eating disorder.

Iris M Balodis, Carlos M Grilo, Marc N Potenza

Abstract readReview
In one paragraph

Review in CNS spectrums, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Iris M Balodis1Department of Psychiatry,Yale University School of Medicine,New Haven,Connecticut,USA.
Carlos M Grilo1Department of Psychiatry,Yale University School of Medicine,New Haven,Connecticut,USA.
Marc N Potenza1Department of Psychiatry,Yale University School of Medicine,New Haven,Connecticut,USA.

Funding

Translational Research of Cocaine, Striatum, and ImpulsivitiesP20DA027844 · NIDA · YALE UNIVERSITY · PI TAYLOR, JANE R · 2010 to 2013
$3.6M
Mid-Career Investigator Award in Eating and WeightK24DK070052 · NIDDK · YALE UNIVERSITY · PI GRILO, CARLOS M · 2005 to 2015
$1.4M
NIDA NIH HHS P20 DA027844NIDDK NIH HHS K24 DK070052
6 · The paper itself

Abstract

Biobehavioral features associated with binge-eating disorder (BED) have been investigated; however, few systematic reviews to date have described neuroimaging findings from studies of BED. Emerging functional and structural studies support BED as having unique and overlapping neural features as compared with other disorders. Neuroimaging studies provide evidence linking heightened responses to palatable food cues with prefrontal areas, particularly the orbitofrontal cortex (OFC), with specific relationships to hunger and reward-sensitivity measures. While few studies to date have investigated non-food-cue responses; these suggest a generalized hypofunctioning in frontostriatal areas during reward and inhibitory control processes. Early studies applying neuroimaging to treatment efforts suggest that targeting neural function underlying motivational processes may prove important in the treatment of BED.

Indexed as

Binge-Eating DisorderBrainCuesHumansNeuroimagingRewardBinge eating disorderfood cuesneuroimagingobesityorbitofrontal cortexreward processingventral striatum

Identifiers

PMID26530404
PMCPMC4658223

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.